Prediction of antipsychotics efficacy based on a polygenic risk score: a real-world cohort study

Conclusion: PRSresponse defined from GWAS studies is significantly associated with response to antipsychotics in a real-world cohort; however, the results of the sensitivity-specificity analysis preclude its use as a predictive tool in clinical practice.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research