ThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia

CONCLUSION: Taken together, these findings reveal a previously unrecognized role for Cirbp in positively regulating hyperthermia resistance and suggest that thermomiR-377-3p and its target gene Cirbp represent promising targets for therapeutic hyperthermia.PMID:38419081 | DOI:10.1186/s13046-024-02983-3

Source: Cell Research - February 28, 2024 Category: Cytology Authors: Tao-Yan Lin Jun-Shuang Jia Wei-Ren Luo Xiao-Lin Lin Sheng-Jun Xiao Jie Yang Jia-Wei Xia Chen Zhou Zhi-Hao Zhou Shu-Jun Lin Qi-Wen Li Zhi-Zhi Yang Ye Lei Wen-Qing Yang Hong-Fen Shen Shi-Hao Huang Sheng-Chun Wang Lin-Bei Chen Yu-Lin Yang Shu-Wen Xue Yong-Lo Source Type: research