An Infant-Type Hemispheric Glioma With SOX5::ALK: A Novel Fusion

In conclusion, we identified a case of congenital IHG with a novel SOX5::ALK fusion that had progressed after chemotherapy and showed partial response and clinical benefit after treatment with the CNS-active ALK inhibitor lorlatinib.PMID:38394779 | DOI:10.6004/jnccn.2023.7102

Source: Journal of the National Comprehensive Cancer Network : JNCCN - February 23, 2024 Category: Cancer & Oncology Authors: Chia Chin Tsai Man-Hsu Huang Chia-Lang Fang Kevin Li-Chun Hsieh Tsung-Han Hsieh Wan-Ling Ho Hsi Chang Min-Lan Tsai Yu-Chien Kao James S Miser Tai-Tong Wong Min-Yu Su Yen-Lin Liu Source Type: research