Construction of an Immune-Related Prognostic Signature and lncRNA ‒miRNA-mRNA ceRNA Network in Acute Myeloid Leukaemia

This study offers innovative insights for AML diagnosis and treatment through a novel immune-related signature and ceRNA axis. Identified novel biomarkers, including two mRNAs (CKLF, PNOC), one miRNA (hsa-miR-323a-3p), and ten lncRNAs (SNHG25, LINC01857, AL390728.6, AC127024.5, Z83843.1, AP002884.1, AC007038.1, AC112512, AC020659.1, AC005921.3) present promising candidates as potential targets for precision medicine, contributing to the ongoing advancements in the field.PMID:38393298 | DOI:10.1093/jleuko/qiae041

Source: Journal of Leukocyte Biology - February 23, 2024 Category: Hematology Authors: Ling Qin Boya Li Shijie Wang Yulai Tang Aamir Fahira Yanqi Kou Tong Li Zhigang Hu Zunnan Huang Source Type: research