Schizandrin A induces non ‐small cell lung cancer apoptosis by suppressing the epidermal growth factor receptor activation

ConclusionsNetwork pharmacology analyses suggested that ERBB family members may be the targets of SchA. SchA can inhibit NSCLC at least in part by inhibiting EGFR phosphorylation, and activating the EGFR bypass can neutralize the cytotoxicity of SchA.

Source: Cancer Medicine - February 20, 2024 Category: Cancer & Oncology Authors: Linhai Zhu, Yanye Wang, Xuhua Huang, Xide Liu, Bo Ye, Yi He, Haojie Yu, Wang Lv, Luming Wang, Jian Hu Tags: RESEARCH ARTICLE Source Type: research