Identification and validation of stemness-based and ferroptosis-related molecular clusters in pancreatic ductal adenocarcinoma

In conclusion, we developed a stemness-based and ferroptosis-related prognostic model, which could help predict overall survival for PDAC patients. Targeting ferroptosis may be a promising therapeutic strategy to inhibit PDAC progression by suppressing CSCs.PMID:38262107 | PMC:PMC10832490 | DOI:10.1016/j.tranon.2024.101877

Source: Translational Oncology - January 23, 2024 Category: Cancer & Oncology Authors: Shiye Ruan Hailiang Wang Zhongyan Zhang Qian Yan Yubin Chen Jinwei Cui Shanzhou Huang Qi Zhou Chuanzhao Zhang Baohua Hou Source Type: research