Investigate the Therapeutic Effect of Ibandronate Sodium on Knee Osteoarthritis Based on TLRs/MyD88/NF- κB Signaling Pathway < em > in Vitro < /em > and < em > in Vivo < /em >

CONCLUSIONS: Ibandronate sodium demonstrates a protective effect on articular chondrocytes and exhibits the potential to decelerate the pathological progression of knee osteoarthritis (KOA) in rats. This mechanism is likely achieved through the inhibition of the TLRs/MyD88/NF-κB signaling pathway.PMID:38273750 | DOI:10.24976/Discov.Med.202436180.9

Source: Discovery Medicine - January 26, 2024 Category: Research Authors: Mingxing Luo Qingze Wang Junguo Bao Source Type: research