Treatment Response to Neoadjuvant Therapy in Squamous Esophageal Cancer —Correlation Between Metabolic Response and Histopathology

ConclusionOur study confirms the correlation of post neoadjuvant chemotherapy PET SUV with histopathological response, the cut-off of SUV being 5.05 in our cohort. This confirms the predictive value of FDG PET as demonstrated in other studies. Furthermore, its prognostic value with respect to survival has been verified in multiple other studies. With larger scale randomized studies, we may be able to identify the group of patients who have borderline operability anatomically as well as physiologically, where alternative treatment regimens may be indicated to improve outcomes.
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research