Tempol treatment normalizes membrane expression of epithelial transport proteins in the kidney of salt-loaded hypertensive diabetic db/db mice

CONCLUSIONS: This study demonstrates that tempol down-regulates epithelial transport mechanisms in each segment of the nephron and normalizes salt-induced high blood pressure in diabetic animals presumably in a PKC dependent manner.PMID:38186979 | PMC:PMC10767517

Source: American Journal of Translational Research - January 8, 2024 Category: Research Authors: Yunus E Dogan Niharika Bala Kevin M Chacko Kubra M Tuna Abdel A Alli Source Type: research