An overview of CFTR mutation profiles and assisted reproductive technology outcomes in Chinese  patients with congenital obstructive azoospermia

ConclusionApart from the IVS9-5T mutation, the genetic mutation pattern ofCFTR in Chinese OA patients is heterogeneous, which is significantly different from that of Caucasians. Although carrying twoCFTR mutations or not had no effect on the pregnancy outcomes in OA patients after ICSI, genetic counseling is still recommended for such patients.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research