Best step-up treatments for children with uncontrolled asthma: a systematic review and network meta-analysis of individual participant data

Conclusions
Uncontrolled children/adolescents on low-dose ICS should be recommended a change to medium-dose ICS+LABA to reduce the risk for exacerbation and improve lung function.

Source: European Respiratory Journal - December 21, 2023 Category: Respiratory Medicine Authors: Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Culeddu, G., Hughes, D. A., Turner, S., Tudur Smith, C., on behalf of the EINSTEIN Collaborative Group Tags: Asthma and allergy Original Articles: Asthma Source Type: research