Endocrine-disrupting chemicals and neurodevelopment in children

The endocrine system plays a crucial role in the neurodevelopment of children. Starting from the prenatal period, maternal hormones, particularly thyroid hormones and glucocorticoids, significantly influence fetal brain development and psychomotor development following birth.1 Thyroid hormones are critical for normal neurogenesis, neuronal migration, differentiation of neuronal and glial cells, myelination, and synaptogenesis.1 Their deficiency can impair central nervous system development. Maternal hyperthyroidism poses a risk for attention deficit/hyperactivity disorder in the fetus, whereas maternal hypothyroidism increases the risk of autism spectrum disorder.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Editorial Source Type: research