Macromolecular Complex Including MLL3, Carabin and Calcineurin Regulates Cardiac Remodeling

CONCLUSIONS: Our study reveals an unsuspected epigenetic mechanism of CaN that directly regulates MLL3 histone methyl transferase activity to promote cardiac remodeling.PMID:38084599 | DOI:10.1161/CIRCRESAHA.123.323458

Source: Circulation Research - December 12, 2023 Category: Cardiology Authors: Roberto Pane Loubna Laib Karina Formoso Maximin D étrait Yannis Sainte-Marie Florence Bourgailh Nolan Ruffenach Hanam ée Faugeras Ilias Simon Emeline Lhuillier Frank Lezoualc'h Caroline Conte Source Type: research