Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction

CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | DOI:10.1590/1678-7757-2023-0209

Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research