CCR8 as a Therapeutic Novel Target: Omics-Integrated Comprehensive Analysis for Systematically Prioritizing Indications
In this study, we conducted an extensive bioinformatics analysis integrating genomics, proteomics, and transcriptomics data to establish CCR8 as a promising anti-cancer drug target. Our approach encompassed data collection from diverse knowledge resources, gene function analysis, differential gene expression profiling, immune cell infiltration assessment, and strategic prioritization of target indications. Our findings revealed strong correlations between CCR8 and specific cancers, notably Breast Invasive Carcinoma (BRCA), Colon Adenocarcinoma (COAD), Head and Neck Squamous Cell Carcinoma (HNSC), Rectum adenocarcinoma (READ), Stomach adenocarcinoma (STAD), and Thyroid carcinoma (THCA). This research advances our understanding of CCR8 as a potential target for anti-cancer drug development, bridging the gap between molecular insights and creating opportunities for personalized treatment of solid tumors.PMID:38001911 | DOI:10.3390/biomedicines11112910
Source: Genomics Proteomics ... - Category: Genetics & Stem Cells Authors: Nari Kim Mi-Hyun Kim Junhee Pyo Soo-Min Lee Ji-Sung Jang Do-Wan Lee Kyung Won Kim Source Type: research
More News: Adenocarcinoma | Breast Carcinoma | Cancer | Cancer & Oncology | Carcinoma | Colon Cancer | Colorectal Cancer | Gastric (Stomach) Cancer | Genetics | Head and Neck Cancer | HNSCC | Skin Cancer | Squamous Cell Carcinoma | Study | Thyroid | Thyroid Cancer