Association between NOS3 gene polymorphisms and genetic susceptibility to congenital heart Disease: A systematic review and meta-analysis

CONCLUSION: rs1799983 (G894T) and rs7830 (G10T) polymorphic sites might play a role in the susceptibility of sporadic congenital heart disease and increase the risk of CHD. Yet, it is still necessary to expand the sample size and conduct more prospective/retrospective studies to confirm whether the rs2070744 (T-786C) polymorphism tended to increase the incidence of CHD.PMID:37952311 | DOI:10.1016/j.cyto.2023.156415

Source: Cytokine - November 12, 2023 Category: Molecular Biology Authors: Kang Yi Wei Wang Xin Zhang Xin Dong Zhengye Fan Yuhu Ma Jie Gao Xinyao Li Tao You Source Type: research