Inhalable chitosan-based hydrogel as a mucosal adjuvant for hydroxychloroquine in the treatment for SARS-CoV-2 infection in a hamster model

CONCLUSION: In hamsters infected with the SARS-CoV-2 virus, the combination of intranasal COS and HCQ was associated with increased HCQ absorption in the lungs, more effective immune responses, without increasing the risk of hepatic or cardiac injuries.PMID:37620239 | DOI:10.1016/j.jmii.2023.08.001

Source: Journal of Microbiology, Immunology, and Infection - August 24, 2023 Category: Microbiology Authors: Donna Shu-Han Lin Shian Chiuan Tzeng Tai-Lung Cha Chin-Mao Hung Wen-Chin Lin Chuen-Mi Yang Hsuan-Ying Lu Jia-Yu Chang Shu-Wei Huang Source Type: research