Altered endosomal-lysosomal biogenesis in melanoma

This study demonstrated the dysregulation of Syntenin-1, Sortilin and Rab25 may provide a differentiating feature between cutaneous melanoma and squamous cell carcinoma, while IGF2R may indicate malignant propensity in these skin cancers.PMID:37562257 | DOI:10.1016/j.neo.2023.100924

Source: Neoplasia - August 10, 2023 Category: Cancer & Oncology Authors: Giang T Lam Alexandra Sorvina Carmela Martini Sarita Prabhakaran Ben S-Y Ung Joanna Lazniewska Courtney R Moore Andrew R Beck Ashley M Hopkins Ian R D Johnson Maria C Caruso Shane M Hickey Robert D Brooks Louise Jackett Litsa Karageorgos Erwin J Foster-Sm Source Type: research