Fat ‐Diets in Perinatal Stages Altered Nr3c2‐Mediated Ca2+ Currents in Mesenteric Arteries of Offspring Rats

ConclusionThe results firstly demonstrate that aldosterone-receptor activation can stimulate Ca2+ currents via LTCC in vascular myocytes, which can be altered by perinatal foods via epigenetic changes of DNA methylation in the promoters of Nr3c2 and LTCC.

Source: Molecular Nutrition and Food Research - June 28, 2023 Category: Food Science Authors: Qiutong Zheng, Na Li, Yingying Zhang, Jingyang Li, Eryun Zhang, Zhice Xu Tags: Research Article Source Type: research