Prevalence, capsular types, antimicrobial resistance and risk factors associated with pneumococcal carriage among children after long-term 10-valent pneumococcal conjugate vaccine use in Brazil

CONCLUSIONS: Long-term universal childhood use of PCV10 has nearly eliminated carriage with PCV10 serotypes, but the high frequency of MDR isolates, especially associated with serotype 6C/D, remains a concern. Replacing PCV10 with PCV13 should reduce the proportion of ERY-R isolates and PNSP by at least 14% and 18%, respectively.PMID:37061371 | DOI:10.1016/j.vaccine.2023.04.023

Source: Vaccine - April 15, 2023 Category: Allergy & Immunology Authors: Let ícia B D P Fortuna Filipe M Miranda Isa M F Antunes Amanda B Silva Amanda S Cabral Ítalo M Dolores Nayara T Cardoso-Marques L úcia M Teixeira Felipe P G Neves Source Type: research