BCG Aortitis, a Rare Complication of BCG Therapy

This report presents a rare case of BCGaortitis treated in a tertiary care centre.REPORT: A 74 year old man, with a history of bladder cancer treated with BCG therapy over a year ago, presented with malaise, abdominal pain, anorexia, and significant weight loss for several months associated with acute on chronic renal failure and a tender aneurysm. He was diagnosed with hepatic BCGitis and pararenal BCGaortitis. He was considered too high risk for open surgery after a multidisciplinary team meeting and was treated with a four vessel physician modified endograft (PMEG) and antituberculous therapy. At seven month follow up, he was clinically well and control computed tomography showed a patent endograft with complete exclusion of the aortic aneurysm.DISCUSSION: Infectious BCG complications after intravesical BCG administration for in situ bladder carcinomas can lead to severe early and late complications. In the present case, the patient presented with both liver and aortic BCG infection. The lack of positive microbiological data should not discourage clinicians from considering BCG infection even if several months have passed since the last BCG instillation.PMID:36949865 | PMC:PMC10025951 | DOI:10.1016/j.ejvsvf.2023.02.003

Source: Pain Physician - March 23, 2023 Category: Anesthesiology Authors: Joseph Haddad Hortense Chalret du Rieu Eric Ducasse Xavier Berard Caroline Caradu Source Type: research