Suitability of Goal Attainment Scaling in Older Adult Populations with Neurodegenerative Disease Experiencing Cognitive Impairment: A Systematic Review and Meta-Analysis

This study conducted a systematic review to evaluate the suitability of GAS as an outcome measure for older adult populations with neurodegenerative disease experiencing dementia or cognitive impairment, based on responsiveness. Methods: The review was registered with PROSPERO and performed by searching ten electronic scientific databases (PubMed, Medline OVID, CINAHL, Cochrane, Embase, Web of Science, PsychINFO, Scopus, OTSeeker, RehabDATA) and four registries (Clinicaltrials.gov, Grey Literature Report, Mednar, Open Gre y). A summary measure of responsiveness (post-intervention minus pre-intervention mean GAS T-score) was compared across eligible studies using a random-effects meta-analysis. Risk of bias in included studies was assessed using the NIH Quality Assessment Tool for Before-After (Pre-Post) Studies with No Control Group. Results: 882 eligible articles were identified and screened by two independent reviewers. Ten studies met inclusion criteria for the final analysis. Of the ten included reports, 3 focus on all-cause dementia, 3 on Multiple Sclerosis, 1 on Parkinson’s Disease, 1 on Mild Cognitiv e Impairment, 1 on Alzheimer’s Disease, and 1 on Primary Progressive Aphasia. Responsiveness analyses showed pre- and post-intervention GAS goals were significantly different from zero (Z=7.48, p
Source: Gerontology - Category: Geriatrics Source Type: research