MTA1 as negative prognostic marker in vulvar carcinoma

CONCLUSIONS: MTA1 was identified as a negative prognostic marker for vulvar carcinoma associated with advanced tumor stage and FIGO grading. A possible explanation could be that the antibody used for this study does not bind to a possible mutation in the C terminal region of MTA leading to negative immunohistochemical staining and this can be correlated with early recurrence in patients with vulvar carcinoma.PMID:36689059 | DOI:10.1007/s00432-023-04579-4

Source: Clinical Breast Cancer - January 23, 2023 Category: Cancer & Oncology Authors: Giulia Wanka Julia Jueckstock Carl Mathis Wild Aurelia Vattai Sophie F ürst Helene H Heidegger Christina Kuhn Elisa Schmoeckel Udo Jeschke Christian Dannecker Source Type: research