Preclinical Identification Of Tumor-Draining Lymph Nodes Using a Multimodal Non-invasive In vivo Imaging Approach

ConclusionsWhen taken together, our results demonstrate the feasibility of18F-FDG-PET/MRI as a valid method for non-invasivein vivo, intraoperative, andex vivo identification of the lymphatic drainage and glucose metabolism within the TDLNs. In addition, using Patent Blue V provides additive value for the macroscopic localization of the lymphatic drainage both visually and byex vivo optical imaging analysis. Thus, both methods are valuable, easy to implement, and cost-effective for preclinical identification of the TDLN.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research