Morphine Versus Oxycodone for Cancer Pain Using a Catechol-O-methyltransferase Genotype Biomarker: A Multicenter, Randomized, Open-Label, Phase III Clinical Trial (RELIEF Study)

CONCLUSION: Using the COMT rs4680 genotype alone is not recommended for selecting between morphine and oxycodone for pain relief.PMID:36426809 | DOI:10.1093/oncolo/oyac233

Source: The Oncologist - November 25, 2022 Category: Cancer & Oncology Authors: Hiromichi Matsuoka Junji Tsurutani Yasutaka Chiba Yoshihiko Fujita Kiyohiro Sakai Takeshi Yoshida Miki Nakura Ryo Sakamoto Chihiro Makimura Yoichi Ohtake Kaoru Tanaka Hidetoshi Hayashi Masayuki Takeda Tatsuya Okuno Naoki Takegawa Koji Haratani Atsuko Koya Source Type: research