Cardiovascular outcomes in children with Kawasaki disease: a population-based cohort study

CONCLUSION: KD survivors are at increased risk of post-discharge cardiovascular events but have a lower risk of death, which justifies enhanced cardiovascular disease surveillance in these patients.IMPACT: Among 4597 Kawasaki disease (KD) survivors, 79 (1.7%) experienced major adverse cardiac events (MACE) and 632 (13.8%) had composite cardiovascular events during 11-year median follow-up. KD survivors had significantly higher risks of post-discharge MACE and cardiovascular events versus non-exposed children. Only nine KD survivors (0.2%) died during follow-up, and the risk of mortality was significantly lower among KD survivors versus non-exposed children. Childhood KD survivors should receive preventative counseling and cardiovascular surveillance, aiming to mitigate adult cardiovascular disease.PMID:36380069 | DOI:10.1038/s41390-022-02391-3

Source: Pediatric Research - November 15, 2022 Category: Pediatrics Authors: Cal Robinson Rahul Chanchlani Anastasia Gayowsky Sandeep Brar Elizabeth Darling Catherine Demers Tapas Mondal Rulan Parekh Hsien Seow Michelle Batthish Source Type: research