Sickle cells are not necessarily protective against falciparum- A case report
We report an unusual case of a child with homozygous SCD presenting with falciparum malaria and had hyper parasitemia and severe anemia which completely resolved following treatment. Clinical suspicion in our case arose considering the endemic nature of malaria in our country. The two overlapping injuries to spleen reduced the clearance of parasites by the spleen as evidenced by high parasite load. Our case report reinforces malaria as a cause of clinical worsening of SCD and highlights the importance of a multifactorial approach in the management of worsening anemia in SCD.
Source: Asian Journal of Transfusion Science - Category: Hematology Authors: Jess Elizabeth Rasalam Snehil Kumar K Sujith NA Fouzia Arpana Palle Dolly Daniel Sukesh Chandran Nair Source Type: research
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