Lifestyle factors and development and natural course of gastroenteropancreatic neuroendocrine tumors (GEP-NETs): a review of the literature

Conclusion: Different tissues, i.e., pancreas and small intestine, may respond differently to exposure to alcohol and smoking. Evidence for diet so far is too limited to draw conclusions. Diabetes seems to be an important risk factor for the development of pancreatic NET w ith a protective role in disease progression, while BMI is not unequivocally associated with development and prognosis of NETs. Hence, our findings suggest that lifestyle factors play an important role in NET development as disease course. Future research should consider lifestyle as an influence on disease progression and treatment response.
Source: Neuroendocrinology - Category: Endocrinology Source Type: research