Diagnostic yield of calcofluor white in the identification of Candida albicans in oral squamous cell carcinoma

Conclusion: Our results show minimal agreement with PAS with a Kappa score of 0.148 (95% CI = 0.39 to 0.09). Overall detection rate was similar for both the index test and reference standard although there was considerable number of intermediate test results. Sensitivity of CFW was comparable to that of earlier studies but specificity was low and the degree of concordance was 60.4%. Although CFW staining can come with high false positive they are a useful test for ruling out candida infection when the test result is negative.

Source: Journal of Oral and Maxillofacial Pathology - October 17, 2022 Category: ENT & OMF Authors: Alagesan Chinnasamy Karthikeyan Ramalingam Sushruth Nayak Vikranth Rai Vidhya Gopinath Gurveen Chawla Source Type: research