Infusion of two-dose mesenchymal stem cells is more effective than a single dose in a dilated cardiomyopathy rat model by upregulating indoleamine 2,3-dioxygenase expression

CONCLUSIONS: Administration of two-dose hUCMSCs has better therapeutic effects than single-dose therapy for inhibiting myocardial inflammation to improve LV function in DCM rats. These effects are associated with upregulating IDO expression and its systemic anti-inflammatory activities.PMID:35962420 | DOI:10.1186/s13287-022-03101-w

Source: Cell Research - August 12, 2022 Category: Cytology Authors: Chenyi Gong Lei Chang Xuan Sun Yu Qi Rong Huang Ke Chen Bin Wang Lina Kang Lian Wang Biao Xu Source Type: research