Aromatase Inhibition Increases Blood Pressure and Markers of Renal Injury in Female Rats

In conclusion, chronic aromatase inhibition in vivo with ASZ increases blood pressure and markers of renal proximal tubular injury in female Sprague Dawley rats, suggesting an important role for aromatization in the maintenance cardiovascular and renal health in females.PMID:35900340 | DOI:10.1152/ajprenal.00055.2022

Source: Am J Physiol Renal P... - July 28, 2022 Category: Urology & Nephrology Authors: Rawan N Almutlaq Annie E Newell-Fugate Louise Christine Evans Huma Fatima Eman Y Gohar Source Type: research