Tranexamic acid is not inferior to placebo with respect to adverse events in suspected traumatic brain injury patients not in shock with a normal head computed tomography scan: A retrospective study of a randomized trial
CONCLUSION
Administration of either a 2-g TXA bolus or a 1-g TXA bolus plus 1-g TXA 8-hour infusion in suspected TBIs without ICH is not associated with increased adverse events or unfavorable outcomes. Because the out-of-hospital 2-g bolus is associated with a mortality benefit, it should be administered in suspected TBI.
LEVEL OF EVIDENCE
Therapeutic/Care Management; Level II.
Source: The Journal of Trauma: Injury, Infection, and Critical Care - Category: Orthopaedics Tags: 2022 EAST QUICK SHOT Source Type: research
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