Rapidly Progressive Dementia and Myoclonus with Elevated CSF IgG Index in Young Adult Immigrants: Treatable, but Not Always with Immunosuppression (P2.322)

CONCLUSIONS: Young adults with RPD, myoclonus, and elevated CSF IgG index may have SSPE. Upbringing in areas in which measles eradication had not yet been achieved can be an important diagnostic clue. EEG and measles antibodies in serum and CSF are useful, readily available diagnostic studies. Reports of accelerated disease course associated with steroids, pregnancy, and HIV/AIDS in patients with SSPE support the hypothesis that empiric immunosuppression could have worsened the outcome in these two patients.Disclosure: Dr. Jay has nothing to disclose. Dr. Zimmermann has nothing to disclose. Dr. DaSilva has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Global Neurology Source Type: research