Induced acute hyperglycemia modifies the barrier function of the intestinal epithelium by tissue inflammation and tight junction disruption resulting in hydroelectrolytic secretion in an animal model
This study aimed to evaluate the impact of acute hyperglycemia diabetes on intestinal tight junction proteins, metabolic failure, intestinal ion and water transports, and IEBF parameters. Diabetes was induced in male Rattus norvegicus (200-310 g) with 0.5 mL of streptozotocin (70 mg/kg). Glycemic and clinical parameters were evaluated every 7 days, and intestinal parameters were evaluated on the 14th day. The MetS-D animals showed a clinical pattern of hyperglycemia, with increases in the area of villi and crypts, lactulose:mannitol ratio, myeloperoxidase (MPO) activity, and intestinal tissue concentrations of malondialdeh...
Source: Brazilian Journal of Medical and Biological Research - April 24, 2024 Category: Research Authors: F J W S Siqueira F A P Rodrigues S A Ribeiro H N Veras F C S Ferreira R C L Siqueira A A Dos Santos A Havt A A M Lima Source Type: research
Association of lipid profile and obesity in patients with polycystic ovary syndrome
Conclusion. The results showed that abnormal lipid profile and obesity have a significant association with PCOS patients. Regular monitoring and treatment of PCOS patients are required to reduce the risk of infertility, MetS, and CVD.PMID:38656255 | DOI:10.2478/enr-2024-0009 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Sadaf Parveen Saba Khan Mohammad Mustufa Khan Bhavana Gupta Ausaf Ahmad Roshan Alam Source Type: research
Does worsening metabolic syndrome increase the risk of developing cancer?
Saudi Med J. 2024 Apr;45(4):446.NO ABSTRACTPMID:38657989 (Source: Saudi Medical Journal)
Source: Saudi Medical Journal - April 24, 2024 Category: Middle East Health Source Type: research
Induced acute hyperglycemia modifies the barrier function of the intestinal epithelium by tissue inflammation and tight junction disruption resulting in hydroelectrolytic secretion in an animal model
This study aimed to evaluate the impact of acute hyperglycemia diabetes on intestinal tight junction proteins, metabolic failure, intestinal ion and water transports, and IEBF parameters. Diabetes was induced in male Rattus norvegicus (200-310 g) with 0.5 mL of streptozotocin (70 mg/kg). Glycemic and clinical parameters were evaluated every 7 days, and intestinal parameters were evaluated on the 14th day. The MetS-D animals showed a clinical pattern of hyperglycemia, with increases in the area of villi and crypts, lactulose:mannitol ratio, myeloperoxidase (MPO) activity, and intestinal tissue concentrations of malondialdeh...
Source: Braz J Med Biol Res - April 24, 2024 Category: Research Authors: F J W S Siqueira F A P Rodrigues S A Ribeiro H N Veras F C S Ferreira R C L Siqueira A A Dos Santos A Havt A A M Lima Source Type: research
Association of lipid profile and obesity in patients with polycystic ovary syndrome
Conclusion. The results showed that abnormal lipid profile and obesity have a significant association with PCOS patients. Regular monitoring and treatment of PCOS patients are required to reduce the risk of infertility, MetS, and CVD.PMID:38656255 | DOI:10.2478/enr-2024-0009 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Sadaf Parveen Saba Khan Mohammad Mustufa Khan Bhavana Gupta Ausaf Ahmad Roshan Alam Source Type: research
Induced acute hyperglycemia modifies the barrier function of the intestinal epithelium by tissue inflammation and tight junction disruption resulting in hydroelectrolytic secretion in an animal model
This study aimed to evaluate the impact of acute hyperglycemia diabetes on intestinal tight junction proteins, metabolic failure, intestinal ion and water transports, and IEBF parameters. Diabetes was induced in male Rattus norvegicus (200-310 g) with 0.5 mL of streptozotocin (70 mg/kg). Glycemic and clinical parameters were evaluated every 7 days, and intestinal parameters were evaluated on the 14th day. The MetS-D animals showed a clinical pattern of hyperglycemia, with increases in the area of villi and crypts, lactulose:mannitol ratio, myeloperoxidase (MPO) activity, and intestinal tissue concentrations of malondialdeh...
Source: Brazilian Journal of Medical and Biological Research - April 24, 2024 Category: Research Authors: F J W S Siqueira F A P Rodrigues S A Ribeiro H N Veras F C S Ferreira R C L Siqueira A A Dos Santos A Havt A A M Lima Source Type: research
Induced acute hyperglycemia modifies the barrier function of the intestinal epithelium by tissue inflammation and tight junction disruption resulting in hydroelectrolytic secretion in an animal model
This study aimed to evaluate the impact of acute hyperglycemia diabetes on intestinal tight junction proteins, metabolic failure, intestinal ion and water transports, and IEBF parameters. Diabetes was induced in male Rattus norvegicus (200-310 g) with 0.5 mL of streptozotocin (70 mg/kg). Glycemic and clinical parameters were evaluated every 7 days, and intestinal parameters were evaluated on the 14th day. The MetS-D animals showed a clinical pattern of hyperglycemia, with increases in the area of villi and crypts, lactulose:mannitol ratio, myeloperoxidase (MPO) activity, and intestinal tissue concentrations of malondialdeh...
Source: Braz J Med Biol Res - April 24, 2024 Category: Research Authors: F J W S Siqueira F A P Rodrigues S A Ribeiro H N Veras F C S Ferreira R C L Siqueira A A Dos Santos A Havt A A M Lima Source Type: research
Does worsening metabolic syndrome increase the risk of developing cancer?
Saudi Med J. 2024 Apr;45(4):446.NO ABSTRACTPMID:38657989 (Source: Saudi Medical Journal)
Source: Saudi Medical Journal - April 24, 2024 Category: Middle East Health Source Type: research
Induced acute hyperglycemia modifies the barrier function of the intestinal epithelium by tissue inflammation and tight junction disruption resulting in hydroelectrolytic secretion in an animal model
This study aimed to evaluate the impact of acute hyperglycemia diabetes on intestinal tight junction proteins, metabolic failure, intestinal ion and water transports, and IEBF parameters. Diabetes was induced in male Rattus norvegicus (200-310 g) with 0.5 mL of streptozotocin (70 mg/kg). Glycemic and clinical parameters were evaluated every 7 days, and intestinal parameters were evaluated on the 14th day. The MetS-D animals showed a clinical pattern of hyperglycemia, with increases in the area of villi and crypts, lactulose:mannitol ratio, myeloperoxidase (MPO) activity, and intestinal tissue concentrations of malondialdeh...
Source: Braz J Med Biol Res - April 24, 2024 Category: Research Authors: F J W S Siqueira F A P Rodrigues S A Ribeiro H N Veras F C S Ferreira R C L Siqueira A A Dos Santos A Havt A A M Lima Source Type: research
Association of lipid profile and obesity in patients with polycystic ovary syndrome
Conclusion. The results showed that abnormal lipid profile and obesity have a significant association with PCOS patients. Regular monitoring and treatment of PCOS patients are required to reduce the risk of infertility, MetS, and CVD.PMID:38656255 | DOI:10.2478/enr-2024-0009 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Sadaf Parveen Saba Khan Mohammad Mustufa Khan Bhavana Gupta Ausaf Ahmad Roshan Alam Source Type: research
Does worsening metabolic syndrome increase the risk of developing cancer?
Saudi Med J. 2024 Apr;45(4):446.NO ABSTRACTPMID:38657989 (Source: Saudi Medical Journal)
Source: Saudi Medical Journal - April 24, 2024 Category: Middle East Health Source Type: research
The efficacy and safety of GLP-1 receptor agonists in youth with type 2 diabetes: a meta-analysis
Glucagon-like peptide 1 receptor agonists have been proven to be effective in adults with diabetes and children with obesity. However, children with type 2 diabetes constitute an underrepresented subpopulation... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - April 24, 2024 Category: Endocrinology Authors: Louise Buonalumi Tacito Yugar, Luis Gustavo Sedenho-Prado, Isadora Maria Castilho da Silva Ferreira, Cleide Aparecida Moreira Silva, Andrei C. Sposito and Cintia Cercato Tags: Research Source Type: research
Association between triglyceride-glucose related indices with the all-cause and cause-specific mortality among the population with metabolic syndrome
Triglyceride-glucose (TyG) index has been determined to play a role in the onset of metabolic syndrome (MetS). Whether the TyG index and TyG with the combination of obesity indicators are associated with the c... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 24, 2024 Category: Cardiology Authors: Xiaoyuan Wei, Yu Min, Ge Song, Xin Ye and Lei Liu Tags: Research Source Type: research
