Lipids to the Rescue in Pulmonary Fibrosis: Biosynthesis, Bioenergetics or Epigenetics?
Am J Respir Cell Mol Biol. 2024 May 7. doi: 10.1165/rcmb.2024-0187ED. Online ahead of print.NO ABSTRACTPMID:38713058 | DOI:10.1165/rcmb.2024-0187ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 7, 2024 Category: Molecular Biology Authors: Manas Ranjan Gartia Victor J Thannickal Source Type: research

Sodium Houttuyfonate Alleviates MCT-induced Pulmonary Hypertension by Regulating Orai1 and Orai2
In this study, we assessed the contributions of Orai proteins to MCT-enhanced SOCE, [Ca2+]i, and cell proliferation in PASMCs and determined the effect of SH on MCT-PH and the underlying mechanism, focusing on Orai proteins, SOCE, and [Ca2+]i in PASMCs. Our results showed that 1) Orai1 and Orai2 were selectively upregulated in the distal pulmonary arteries (PAs) and the PASMCs of MCT-PH rats. 2) Knockdown of Orai1 or Orai2 reduced SOCE, [Ca2+]i, and cell proliferation without affecting their expression in PASMCs in MCT-PH rats. 3) SH significantly normalized the characteristic parameters in a dose-dependent manner in the M...
Source: American Journal of Respiratory Cell and Molecular Biology - May 6, 2024 Category: Molecular Biology Authors: Jun Zhang Fang Dong Gaojia Ju Xinli Pan Xinwu Mao Xiaowen Zhang Source Type: research

A Tale of Two Cytokines: Interleukin-10 Blocks Interferon- γ in Influenza A Virus- < em > Staphylococcus aureus < /em > Co-Infection
Am J Respir Cell Mol Biol. 2024 May 3. doi: 10.1165/rcmb.2024-0154ED. Online ahead of print.NO ABSTRACTPMID:38701437 | DOI:10.1165/rcmb.2024-0154ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 3, 2024 Category: Molecular Biology Authors: Christina Sul Eva Nozik Christina Malainou Source Type: research

The Role of TRPV1 in Febrile Seizure Susceptibility: Inflammation, Respiratory Alkalosis and Seizure Threshold
Am J Respir Cell Mol Biol. 2024 May 3. doi: 10.1165/rcmb.2024-0182ED. Online ahead of print.NO ABSTRACTPMID:38701493 | DOI:10.1165/rcmb.2024-0182ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 3, 2024 Category: Molecular Biology Authors: Benjamin W Ackermann Andreas Merkenschlager Source Type: research

A Tale of Two Cytokines: Interleukin-10 Blocks Interferon- γ in Influenza A Virus- < em > Staphylococcus aureus < /em > Co-Infection
Am J Respir Cell Mol Biol. 2024 May 3. doi: 10.1165/rcmb.2024-0154ED. Online ahead of print.NO ABSTRACTPMID:38701437 | DOI:10.1165/rcmb.2024-0154ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 3, 2024 Category: Molecular Biology Authors: Christina Sul Eva Nozik Christina Malainou Source Type: research

The Role of TRPV1 in Febrile Seizure Susceptibility: Inflammation, Respiratory Alkalosis and Seizure Threshold
Am J Respir Cell Mol Biol. 2024 May 3. doi: 10.1165/rcmb.2024-0182ED. Online ahead of print.NO ABSTRACTPMID:38701493 | DOI:10.1165/rcmb.2024-0182ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 3, 2024 Category: Molecular Biology Authors: Benjamin W Ackermann Andreas Merkenschlager Source Type: research

A Tale of Two Cytokines: Interleukin-10 Blocks Interferon- γ in Influenza A Virus- < em > Staphylococcus aureus < /em > Co-Infection
Am J Respir Cell Mol Biol. 2024 May 3. doi: 10.1165/rcmb.2024-0154ED. Online ahead of print.NO ABSTRACTPMID:38701437 | DOI:10.1165/rcmb.2024-0154ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 3, 2024 Category: Molecular Biology Authors: Christina Sul Eva Nozik Christina Malainou Source Type: research

The Role of TRPV1 in Febrile Seizure Susceptibility: Inflammation, Respiratory Alkalosis and Seizure Threshold
Am J Respir Cell Mol Biol. 2024 May 3. doi: 10.1165/rcmb.2024-0182ED. Online ahead of print.NO ABSTRACTPMID:38701493 | DOI:10.1165/rcmb.2024-0182ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 3, 2024 Category: Molecular Biology Authors: Benjamin W Ackermann Andreas Merkenschlager Source Type: research

Monocyte Production of C1q Potentiates CD8 < sup > + < /sup > T Cell Function Following Respiratory Viral Infection
This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).PMID:38696270 | DOI:10.1165/rcmb.2024-0004OC (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 2, 2024 Category: Molecular Biology Authors: Taylor Eddens Olivia B Parks Dequan Lou Li Fan Jorna Sojati Manda Jo Ramsey Lori Schmitt Claudia M Salgado Miguel Reyes-Mugica Alysa Evans Henry M Zou Tim D Oury Craig Byersdorfer Kong Chen John V Williams Source Type: research

Long Story Short: Understanding Isoform-Specific Expression of FAM13A
Am J Respir Cell Mol Biol. 2024 May 2. doi: 10.1165/rcmb.2024-0166ED. Online ahead of print.NO ABSTRACTPMID:38696272 | DOI:10.1165/rcmb.2024-0166ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 2, 2024 Category: Molecular Biology Authors: Cera A McDonald Ryan A Langlois Source Type: research

SRF Overexpression, A Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma
Am J Respir Cell Mol Biol. 2024 May 2. doi: 10.1165/rcmb.2024-0168ED. Online ahead of print.NO ABSTRACTPMID:38696286 | DOI:10.1165/rcmb.2024-0168ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 2, 2024 Category: Molecular Biology Authors: Chun Y Seow Source Type: research

Monocyte Production of C1q Potentiates CD8 < sup > + < /sup > T Cell Function Following Respiratory Viral Infection
This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).PMID:38696270 | DOI:10.1165/rcmb.2024-0004OC (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 2, 2024 Category: Molecular Biology Authors: Taylor Eddens Olivia B Parks Dequan Lou Li Fan Jorna Sojati Manda Jo Ramsey Lori Schmitt Claudia M Salgado Miguel Reyes-Mugica Alysa Evans Henry M Zou Tim D Oury Craig Byersdorfer Kong Chen John V Williams Source Type: research

Long Story Short: Understanding Isoform-Specific Expression of FAM13A
Am J Respir Cell Mol Biol. 2024 May 2. doi: 10.1165/rcmb.2024-0166ED. Online ahead of print.NO ABSTRACTPMID:38696272 | DOI:10.1165/rcmb.2024-0166ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 2, 2024 Category: Molecular Biology Authors: Cera A McDonald Ryan A Langlois Source Type: research

SRF Overexpression, A Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma
Am J Respir Cell Mol Biol. 2024 May 2. doi: 10.1165/rcmb.2024-0168ED. Online ahead of print.NO ABSTRACTPMID:38696286 | DOI:10.1165/rcmb.2024-0168ED (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 2, 2024 Category: Molecular Biology Authors: Chun Y Seow Source Type: research

The GPR84 Antagonist GLPG1205 Reduces Features of Disease in Experimental Severe Asthma
Am J Respir Cell Mol Biol. 2024 May;70(5):424-427. doi: 10.1165/rcmb.2023-0221LE.NO ABSTRACTPMID:38690993 | DOI:10.1165/rcmb.2023-0221LE (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - May 1, 2024 Category: Molecular Biology Authors: Chantal Donovan Andrew E Thorpe Henry M Gomez Olivia R Carroll Min Feng Xu Bai Hui Chen Jay C Horvat Brian G G Oliver Richard Y Kim Source Type: research