Risk of hospitalized depression and intentional self-harm with brand and authorized generic sertraline - Pennap DD, Swain RS, Welch EC, Bohn J, Lyons JG, Dutcher S, Mosholder AD.
BACKGROUND: Recent suggestions of therapeutic inequivalence of brand and generic sertraline have raised concerns about disproportionately higher adverse events among generic users. OBJECTIVE: To assess the impact of confounding in a comparison of t... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Sertraline hydrochloride for reducing impulsive behaviour in male, repeat-violent offenders (ReINVEST): protocol for a phase IV, double-blind, placebo-controlled, randomised clinical trial - Butler T, Schofield PW, Knight L, Ton B, Greenberg D, Scott RJ, Grant L, Keech AC, Gebski V, Jones J, Ellis A, Weatherburn D, Wilhelm K, Jones A, Churchill A, Allnutt S, Mitchell PB, Chappell D, D'Este C, Villa D, Carr V.
INTRODUCTION: Considerable evidence supports an association between poor impulse control (impulsivity) and violent crime. Furthermore, impulsivity and aggression has been associated with reduced levels of serotonergic activity in the brain. Selective serot... (Source: SafetyLit)
Source: SafetyLit - September 6, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Can I Have a Glass of Wine While Taking Sertraline?
Title: Can I Have a Glass of Wine While Taking Sertraline?Category: Health and LivingCreated: 9/3/2021 12:00:00 AMLast Editorial Review: 9/3/2021 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - September 3, 2021 Category: Psychiatry Source Type: news
Physiologically Based Pharmacokinetic Modeling of Sertraline Dosing in Pregnancy
FDA scientists offer quantitative predictive modeling tools, such as physiologically-based pharmacokinetic (PBPK) modeling, to help optimize drug dosing throughout pregnancy. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 17, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Predictors and trajectories of treatment response to SSRIs in patients suffering from PTSD - N øhr AK, Eriksson H, Hobart M, Moltke I, Buller R, Albrechtsen A, Lindgreen S.
We examined predictors and latent classes of SS... (Source: SafetyLit)
Source: SafetyLit - May 13, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Author Q & A: New generation antidepressants for depression in children and adolescents
In this author interview we find out more about this recently published Network Meta-analysis,New generation antidepressants for depression in children and adolescents. Authors Dr. Sarah Hetrick and Nick Meader tell us about this work.What were you trying to find out with this Network Meta-Analysis?We were trying to find out how well newer generation antidepressants work compared with placebo and if some are more effective than others. We wanted to know how these antidepressants affect:symptoms of depression;recovery: no longer meeting diagnostic criteria for major depressive disorder;response or remission: scores on a sca...
Source: Cochrane News and Events - May 11, 2021 Category: Information Technology Authors: Rachel Klabunde Source Type: news
A New Study Points to MDMA as a Powerful Treatment for PTSD
Post-Traumatic Stress Disorder (PTSD), will affect some 26 million Americans at some point in their lives, according to the Department of Veterans Affairs. The condition, characterized by depression, hopelessness, memory problems, difficulty maintaining relationships, and recurrent visions of the trauma-causing event is notoriously hard to treat. Up to a third of people with the condition are still symptomatic 10 years after diagnosis, and the main therapeutic drugs of choice—the selective serotonin reuptake inhibitors sertraline and paroxetine—fail in up to 60% of patients. A study published yesterday, however...
Source: TIME: Health - May 11, 2021 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized Source Type: news
MIND Institute study of anxiety in children with autism now includes online treatment
(University of California - Davis Health) The UC Davis MIND Institute is now offering online treatment appointments as part of its clinical trial known as the STAAR study. The trial will compare the effectiveness of the medication sertraline and cognitive behavioral therapy in treating anxiety in children with autism. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 20, 2021 Category: International Medicine & Public Health Source Type: news
Zoloft enters list of 10 most commonly prescribed drugs in Australia
Increase in women being diagnosed with depression partly behind rise in useAn increase in women being diagnosed with depression is partly behind a significant rise in prescriptions of the antidepressant sertraline – sold under the brand name Zoloft – which is in the list of Australia’s most commonly prescribed drugs for the first time.On Tuesday Australian Prescriberpublished its annual list of the 10 most commonly taken drugs – based on standard daily doses for every 1,000 people in the population each day – along with a list of the 10 most costly drugs to government, and the 10 most common drugs by prescription...
Source: Guardian Unlimited Science - November 30, 2020 Category: Science Authors: Melissa Davey Tags: Health Australia news Pharmaceuticals industry Depression Mental health Heart disease Stroke Psychology Drugs Women's health Source Type: news
Existing antidepressant helps to inhibit growth of cancer cells in lab animals
(KU Leuven) New research has shown that the antidepressant sertraline helps to inhibit the growth of cancer cells. The substance acts on a metabolic addiction that allows different types of cancer to grow. This is shown by a study on cell cultures and lab animals by researchers at KU Leuven. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 17, 2020 Category: Cancer & Oncology Source Type: news
Effect of psychotropic drugs on cortical excitability of patients with major depressive disorders: a transcranial magnetic stimulation study - Khedr EM, Elserogy Y, Fawzy M, Abdelrahman AA, Galal AM, Noaman MM.
Transcranial magnetic stimulation (TMS) can be used to evaluate the effects of pharmacological interventions. The aim of this study was to assess the impact of the selective serotonin reuptake inhibitor, sertraline, and the atypical antipsychotic drugs que... (Source: SafetyLit)
Source: SafetyLit - August 13, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
The FDA Added Zoloft To The Drug Shortage List: Here ’s Why You Don’t Need To Worry Yet
The Federal Drug Administration (FDA) recently added the popular antidepressant Zoloft (Sertraline) to the drug shortage list. While the reasons for the shortage are unclear and likely due to a manufacturing issue, it is important to understand who needs to be concerned and how to best prepare. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 6, 2020 Category: Pharmaceuticals Authors: Jessica Gold, Contributor Tags: Healthcare /healthcare Innovation /innovation Business /business Manufacturing /manufacturing Remove From Breaking Bar remove-from-breaking Source Type: news
Effects of transcranial direct current stimulation using miniaturized devices vs sertraline for depression in Korea: a 6 week, multicenter, randomized, double blind, active-controlled study - Park S, Choi WJ, Kim S, Kim B, Son SJ, Roh D, Kim WJ, Park JY.
We compared the efficacy and safety of transcranial direct current stimulation (tDCS) vs. Sertraline in the treatment of Major Depressive Disorder (MDD) in South Korean participants. This was a multi-center, double blind, active controlled study with non-i... (Source: SafetyLit)
Source: SafetyLit - June 2, 2020 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news
How Artificial Intelligence Can Help Pick the Best Depression Treatments for You
Seeking out help for depression is hard enough. It doesn’t make things any easier that it can take weeks, months or longer of trying different treatments to find something that works. Doctors typically start patients on antidepressants, but they take at least four weeks to start working, and research has shown that only about 30% respond well to the first drug they’re prescribed. “Right now, treatment selection is purely based on trial and error,” says Dr. Madhukar Trivedi, a professor of psychiatry at the University of Texas Southwestern Medical Center.
But promising new research published in Febru...
Source: TIME: Health - February 20, 2020 Category: Consumer Health News Authors: Mandy Oaklander Tags: Uncategorized Artificial Intelligence medicine mental health onetime psychiatry Source Type: news
EEG Signature Predicts Antidepressant Response EEG Signature Predicts Antidepressant Response
A novel artificial intelligence algorithm can accurately predict which patients will respond positively to the antidepressant sertraline, new research shows.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - February 13, 2020 Category: Neurology Tags: Psychiatry News Source Type: news
