Author Q & A: New generation antidepressants for depression in children and adolescents

In this author interview we find out more about this recently published Network Meta-analysis,New generation antidepressants for depression in children and adolescents. Authors Dr. Sarah Hetrick and Nick Meader tell us about this work.What were you trying to find out with this Network Meta-Analysis?We were trying to find out how well newer generation antidepressants work compared with placebo and if some are more effective than others. We wanted to know how these antidepressants affect:symptoms of depression;recovery: no longer meeting diagnostic criteria for major depressive disorder;response or remission: scores on a scale indicating an important reduction in depression or no longer experiencing depression;ability to function in daily life;suicide-related outcomes; andwhether they cause any unwanted effects in children and adolescents.What is included in this review?The review includes randomised controlled trials that test the efficacy of newer generation antidepressants compared with placebo in children and adolescents with depression. New generation antidepressants are those that have been developed recently. They are sometimes referred to as ‘second-‘ and ‘third-generation’ antidepressants; they do not include older formulations (tricyclic antidepressants or monoamine oxidase inhibitors).Who will be most interested in this research?People who support young people with depression, including both family and informal supports as well as clinicians w...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news

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Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Dental Source Type: forums
ConclusionsIncarcerated individuals in Brazil experienced increased mortality from violence, suicide, and communicable diseases. Mortality was heightened following release for all leading causes of death, with particularly high risk of early violent death and elevated all-cause mortality up to 8 years post-release. These disparities may have been underrecognized in Brazil due to underreporting and insufficient data.
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
In this study, a questionnaire survey was conducted by mail among telephone counselors belonging to the Federation of Inochi No Denwa in Japan. The total number of valid responses was 709 (recovery rate: 50.4%). Following an exploratory factor analysis, three factors were extracted: (1) willingness to engage in telephone counseling activities, (2) sense of being burdened by telephone counseling activities, and (3) sense of difficulty in coping. Structural equation modeling, using all the factors, showed that social support and grit were directly related to the willingness to engage in telephone counseling activities, while...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Condition:   Depression Intervention:   Sponsor:   University Hospital, Montpellier Recruiting
Source: - Category: Research Source Type: clinical trials
[New Era] Increased anxiety, rage or irritability, extreme mood swings, expressing hopelessness, change in eating habits, talking or posting about death or wanting to die and emotional distress are some common signs of suicidal thoughts in children.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
The man allegedly responsible for the botched suicide of prominent South Carolina attorney Alex Murdaugh is expected to appear for a...
Source: Reuters: Health - Category: Consumer Health News Source Type: news
Psychiatry Investig. 2021 Sep 17. doi: 10.30773/pi.2021.0122. Online ahead of print.ABSTRACTOBJECTIVE: The risk of suicide is assessed by identifying the relationship between alcohol-use patterns and suicidal ideation in Korean employees.METHODS: The study involved 13,858 employees who underwent workplace mental health screening at the Workplace Mental Health Institute of Kangbuk Samsung Hospital over a 6-year period between 2014 and 2019. Analysis was performed separately for Alcohol Use Disorders Identification Test-Korea (AUDIT-K) items related to the frequency/volume of alcohol consumption (items 1 to 3, AUDIT-C) and t...
Source: Psychiatry Investigation - Category: Psychiatry Authors: Source Type: research
Cyberbullying is a well-established risk factor for suicidal thoughts and behavior in adolescents. However, research examining the differential influence of different forms of cyberbullying on suicidality is limited. This exploratory study investigated the...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: Suicide is a leading cause of death in the US. Lethal means restriction (LMR), which encourages limiting access and reducing the lethality of particular methods of suicide, has been identified as a viable prevention strategy. For this approach ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news
Depression is the most prevalent mental disorder that can lead to suicide. Due to the tendency of people to share their thoughts on social platforms, social data contain valuable information that can be used to identify user's psychological states. In this...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Media, Marketing, and Internet Issues Source Type: news
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