Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Effects of antipsychotics on heart rate in treatment of schizophrenia: a systematic review and meta-analysis
CONCLUSION: Many studies do not report data for cardiac outcomes, but the available evidence indicates that treatment with antipsychotics raises the risk for tachycardia. Therefore, especially patients with cardiac risk factors should be monitored closely during antipsychotic treatment.REGISTRATION: PROSPERO: CRD42014014919.PMID:35774251 | PMC:PMC9237927 | DOI:10.1177/20451253221097261 (Source: Adv Data)
Source: Adv Data - July 1, 2022 Category: Epidemiology Authors: Maximilian Huhn Thomas Arndt Johannes Schneider-Thoma Stefan Leucht Source Type: research

Effects of antipsychotics on heart rate in treatment of schizophrenia: a systematic review and meta-analysis
CONCLUSION: Many studies do not report data for cardiac outcomes, but the available evidence indicates that treatment with antipsychotics raises the risk for tachycardia. Therefore, especially patients with cardiac risk factors should be monitored closely during antipsychotic treatment.REGISTRATION: PROSPERO: CRD42014014919.PMID:35774251 | PMC:PMC9237927 | DOI:10.1177/20451253221097261 (Source: Adv Data)
Source: Adv Data - July 1, 2022 Category: Epidemiology Authors: Maximilian Huhn Thomas Arndt Johannes Schneider-Thoma Stefan Leucht Source Type: research

Successful Ziprasidone Treatment for Resistant Attention-Deficit/Hyperactivity Disorder and Provisional Motor Tic Disorder
No abstract available (Source: American Journal of Therapeutics)
Source: American Journal of Therapeutics - July 1, 2022 Category: Drugs & Pharmacology Tags: Letters to the Editor Source Type: research

Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020
Turk Psikiyatri Derg. 2022 Summer;33(2):146-148. doi: 10.5080/u26315.ABSTRACTDear Editor, The costs of antipsychotic drugs (APDs) used in the treatment of mental disorders with psychosis are mentioned in treatment guidelines (APA 2021, NICE 2014). While the American Psychiatric Association guideline states that every specialist should make decisions according to the rules and conditions of their country and their region, the National Institute of Health and Clinical Excellence guideline emphasizes that drug costs must be taken into consideration in the treatment process. Classical or first-generation antipsychotic drugs (F...
Source: Turkish Journal of Psychiatry - June 22, 2022 Category: Psychiatry Authors: Mustafa Y ıldız Emre Osman Source Type: research

Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020
Turk Psikiyatri Derg. 2022 Summer;33(2):146-148. doi: 10.5080/u26315.ABSTRACTDear Editor, The costs of antipsychotic drugs (APDs) used in the treatment of mental disorders with psychosis are mentioned in treatment guidelines (APA 2021, NICE 2014). While the American Psychiatric Association guideline states that every specialist should make decisions according to the rules and conditions of their country and their region, the National Institute of Health and Clinical Excellence guideline emphasizes that drug costs must be taken into consideration in the treatment process. Classical or first-generation antipsychotic drugs (F...
Source: Turk Psikiyatri Dergisi - June 22, 2022 Category: Psychiatry Authors: Mustafa Y ıldız Emre Osman Source Type: research

Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020
Turk Psikiyatri Derg. 2022 Summer;33(2):146-148. doi: 10.5080/u26315.ABSTRACTDear Editor, The costs of antipsychotic drugs (APDs) used in the treatment of mental disorders with psychosis are mentioned in treatment guidelines (APA 2021, NICE 2014). While the American Psychiatric Association guideline states that every specialist should make decisions according to the rules and conditions of their country and their region, the National Institute of Health and Clinical Excellence guideline emphasizes that drug costs must be taken into consideration in the treatment process. Classical or first-generation antipsychotic drugs (F...
Source: Turkish Journal of Psychiatry - June 22, 2022 Category: Psychiatry Authors: Mustafa Y ıldız Emre Osman Source Type: research

Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020
Turk Psikiyatri Derg. 2022 Summer;33(2):146-148. doi: 10.5080/u26315.ABSTRACTDear Editor, The costs of antipsychotic drugs (APDs) used in the treatment of mental disorders with psychosis are mentioned in treatment guidelines (APA 2021, NICE 2014). While the American Psychiatric Association guideline states that every specialist should make decisions according to the rules and conditions of their country and their region, the National Institute of Health and Clinical Excellence guideline emphasizes that drug costs must be taken into consideration in the treatment process. Classical or first-generation antipsychotic drugs (F...
Source: Turk Psikiyatri Dergisi - June 22, 2022 Category: Psychiatry Authors: Mustafa Y ıldız Emre Osman Source Type: research

Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020
Turk Psikiyatri Derg. 2022 Summer;33(2):146-148. doi: 10.5080/u26315.ABSTRACTDear Editor, The costs of antipsychotic drugs (APDs) used in the treatment of mental disorders with psychosis are mentioned in treatment guidelines (APA 2021, NICE 2014). While the American Psychiatric Association guideline states that every specialist should make decisions according to the rules and conditions of their country and their region, the National Institute of Health and Clinical Excellence guideline emphasizes that drug costs must be taken into consideration in the treatment process. Classical or first-generation antipsychotic drugs (F...
Source: Turkish Journal of Psychiatry - June 22, 2022 Category: Psychiatry Authors: Mustafa Y ıldız Emre Osman Source Type: research