Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research

Long-term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta-analysis
We examined the long-term efficacy of antipsychotic drugs in acutely ill patients using network meta-analysis. We searched the Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded trials of at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change in overall symptoms of schizophrenia; secondary outcomes were all-cause discontinuation; change in positive, negative and depressive symptoms; quality of life, social functioning, weight gain, antiparkinson medication use, akathisia, serum prolactin level, QTc prolongation, and sedation. ...
Source: World Psychiatry - May 9, 2023 Category: Psychiatry Authors: Stefan Leucht Johannes Schneider-Thoma Angelika Burschinski Natalie Peter Dongfang Wang Shimeng Dong Maximilian Huhn Adriani Nikolakopoulou Georgia Salanti John M Davis Source Type: research