Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research

Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
J Fam Pract. 2022 Jul;71(6):E13-E15. doi: 10.12788/jfp.0445.ABSTRACTYES. Augmentation with second generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective in patients with moderate-to-severe depression who have had a suboptimal response to a selective serotonin reuptake inhibitor or a serotonin-norepinephrine reuptake inhibitor (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs] and an individual RCT). Augmenting antidepressant therapy with cariprazine, ziprasidone, or olanzapine also appears to improve depressive symptoms over the shor...
Source: The Journal of Family Practice - August 22, 2022 Category: Practice Management Authors: Heather Bleacher Lindsay Koerperich Naomi Malam Kristen DeSanto Source Type: research