Introduction to Human Plague: Managing Infectious Hazards
World Health Organization. 2017 This 21-minute module is an introductory-level online course on plague, a zoonotic disease with severe clinical presentations caused by the bacterium Yersinia pestis. It describes the transmission cycle of the disease, explains the difference between the bubonic plague and pneumonic plague, and describes the public health concerns of plague. (Video or Multimedia) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - October 4, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Plague Fact Sheet
World Health Organization. 04/2017 This fact sheet provides information about plague, an infectious disease caused by the bacteria Yersinia pestis, a zoonotic bacteria, usually found in small mammals and their fleas. It is transmitted between animals from their fleas. The fact sheet discusses signs and symptoms, where plague is found, diagnosing plague, treatment, prevention, vaccination, managing plague outbreaks, and surveillance and control. (Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - October 2, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

What Is a Yersinia Arthritic Infection?
Title: What Is a Yersinia Arthritic Infection?Category: Doctor's& Expert's views on SymptomsCreated: 8/29/2017 12:00:00 AMLast Editorial Review: 8/29/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - August 29, 2017 Category: Rheumatology Source Type: news

There ’ s plague in Arizona. Authorities warn of fleas that can infect people and pets.
Public health officials in two Arizona counties are warning residents about the discovery of plague bacteria, an endemic concern among those who live in the American Southwest but unsettling nonetheless, given the disease's devastating impact on human history. Navajo and Coconino counties are adjacent to one another, and in each community the findings are identical: Fleas carrying yersinia […]Related:5 dead after FDA-approved obesity treatment that places silicone balloon in stomach, agency saysA sleeping mother suffocated her newborn in the maternity ward. Now she’s suing the hospital.Trump declares the opi...
Source: Washington Post: To Your Health - August 15, 2017 Category: Consumer Health News Source Type: news

What Conditions is Erythema Nodosum Associated With?
Discussion Erythema nodosum (EN) is a common dermatological eruption characterized by inflammatory nodules of the subcutaneous fat (panniculitis) on the extensor surfaces of the extremities especially the shins, thighs, and forearms. They are usually painful, nodular, bilateral and multiple. They can be found on other areas and be unilateral. They can be red, purple or blackish. They usually resolve without problems in 3-6 weeks. Diagnosis is usually clinical but biopsy may be needed if there is atypical presentation or history, physical examination or laboratory testing reveals potential underlying diseases. Treatment is...
Source: PediatricEducation.org - July 24, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Plague bacteria take refuge in amoebae
Yersinia pestis, the bacterium that causes bubonic plague, can survive within the ubiquitous soil protozoan, the amoeba, by producing proteins that protect against the latter microbe ' s digestion, report scientists. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 29, 2017 Category: Science Source Type: news

A vaccine against the plague? This Maryland company is on it
A subsidiary of Falls Church-based government IT firm CSRA Inc. (NYSE: CSRA) has received a nod from the Food and Drug Administration for the vaccine it is developing against the bubonic plague. Yes, the plague. Frederick-based DynPort Vaccine Company LLC was granted Orphan Drug Designation from the FDA for the vaccine it is creating for the U.S. Department of Defense. It is intended for pre-exposure prophylaxis to combat the infection from Yersinia pestis, which is the causative agent o f the bubonic… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 9, 2017 Category: Pharmaceuticals Authors: Tina Reed Source Type: news

Frozen chemistry controls bacterial infections
Chemists and molecular biologists have made an unexpected discovery in infection biology. The researchers can now show that two proteins that bind to one another slow down a chemical reaction central to the course of the disease in the bacteria Yersinia pseudotuberculosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 3, 2017 Category: Science Source Type: news

Frozen chemistry controls bacterial infections
(Umea University) Chemists and molecular biologists have made an unexpected discovery in infection biology. The researchers can now show that two proteins that bind to one another slow down a chemical reaction central to the course of the disease in the bacteria Yersinia pseudotuberculosis. The results have been published in the Journal of Biological Chemistry. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 3, 2017 Category: Biology Source Type: news

Interim-Planning Guidance for the Handling of Solid Waste Contaminated with a Category A Infectious Substance
U.S. Department of Transportation. 01/19/2017 This 82-page document provides federal guidance for the safe handling of solid waste contaminated with a Category A infectious substance and the proper management of inactivated Category A waste materials in the United States. An infectious substance meets Category A criteria if it is in a form capable of causing permanent disability or life-threatening or fatal disease in otherwise healthy humans or animals upon exposure to the substance (such as Ebola virus, Yersinia pestis, or Bacillus anthracis). (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 23, 2017 Category: Global & Universal Authors: The U.S. National Library of Medicine Source Type: news

Race to make vaccine for the PLAGUE amid fears terrorists could use it to kill millions
Researchers at the University of Texas, backed by the Department of Defense, warn Yersinia pestis is one of the most likely candidates for a bioweapon. (Source: the Mail online | Health)
Source: the Mail online | Health - January 14, 2017 Category: Consumer Health News Source Type: news

Race to make vaccine for the PLAGUE amid fears terrorists could be turning it into a weapon to wipe out millions
Researchers at the University of Texas, backed by the Department of Defense, warn Yersinia pestis is one of the most likely candidates for a bioweapon. (Source: the Mail online | Health)
Source: the Mail online | Health - January 13, 2017 Category: Consumer Health News Source Type: news

Reconstructing the 6th century plague from a victim
(Molecular Biology and Evolution (Oxford University Press)) Scientists based in Germany, including Michal Feldman, Johannes Krause, Michaela Harbeck and colleagues have confirmed the bacterial culprit of the plague from sixth century skeletons found in Altenerding, an ancient southern German burial site near Munich. The Altenerding genome dates back to the very beginning of the plague. They have generated the first high-coverage genome of the bacterial agent responsible for the Justinian plague, in addition to revealing new insights in the molecular evolution of Yersinia pestis since the Byzantine era. (Source: EurekAlert!...
Source: EurekAlert! - Infectious and Emerging Diseases - August 30, 2016 Category: Infectious Diseases Source Type: news

Bacteria can multiply disease-inducing genes to rapidly cause infection
More than 22 years ago, researchers discovered an infection strategy of human pathogenic Yersinia bacteria -- a protein structure in bacterial cell-walls that resembled a syringe. The structure, named "Type III secretion system" or T3SS, makes it possible to transfer bacterial proteins into the host cell and destroy its metabolism. After the discovery, researchers have found T3SS in several other bacteria species and T3SS has proven to be a common infection mechanism that pathogens, i.e. an infectious agent such as a virus or bacterium, use to destroy host cells. Now researchers have found a link between infection and rapi...
Source: ScienceDaily Headlines - July 1, 2016 Category: Science Source Type: news

[In Depth] How Europe exported the Black Death
Black Death—the bubonic plague—probably reached Europe from Asia in 1346, and later outbreaks were thought to have arrived from the east via a similar route. Now, scientists have evidence that a virulent strain of the Black Death bacterium lurked for centuries in Europe while also working its way back to Asia. At the recent Society for American Archaeology meeting, researchers reported analyzing the remains of medieval victims in London; Barcelona, Spain; and near the Volga River in Russia. They determined that the victims all died of a highly similar strain of Yersinia pestis, the plague bacterium, which had mutated i...
Source: ScienceNOW - April 28, 2016 Category: Science Authors: Andrew Lawler Tags: Ancient DNA Source Type: news