PGS/PGD/PGT testing can reduce pregnancy rates
Many IVF-clinic websites are selling PGS / PGD/ PGT - preimplantation genetic testing to their patients , by claiming that : It increases pregnancy success rates, lowers the risk of miscarriage, and avoids the time (and expense) of multiple IVF cycles. However, the website of Britain ’s Human Fertilisation and Embryology Authority, which regulates IVF medicine in the U.K., clearly states - that there is “limited evidence” for those claims.The dilemma posed by mosaic embryos has muddied the water so much that Pasquale Patrizio, head of fertility medicine at Yale University, and Sherman Silber of St. Luke ’s Hos...
Source: Dr.Malpani's Blog - December 31, 2018 Category: Reproduction Medicine Source Type: blogs

Increased Payer and Provider Support May Drive Billions of Dollars in Savings from Biosimilars
By SHEILA FRAME  FDA Commissioner Scott Gottlieb has said biosimilars are “key to promoting access and reducing health care costs. And it’s a key to advancing public health.” While the Administration works to reduce barriers to bringing biosimilars to market, payers and providers can help increase adoption of biosimilars in clinical practice and ensure cost savings. Organizations such as the American College of Rheumatology and the American Society of Clinical Oncology have issued educational documents to help guide providers in incorporating biosimilars into treatment plans, where appropriate. Yet, many doctors re...
Source: The Health Care Blog - December 20, 2018 Category: Consumer Health News Authors: matthew holt Tags: Pharmaceuticals biologics biosimilars Sheila Frame Source Type: blogs

Creating a Google Earth of the Brain
A recentNew York Times article describes a $50 million project by more than a dozen research centers aiming to create a sort ofGoogle Earth of the brain. In a series of 11 papers, published in Science and related journals, a consortium of researchers has produced the most richly detailed model of the brain ’s genetic landscape to date, one that incorporates not only genes but also gene regulators, cellular data and developmental information across the human life span.The PsychENCODE Consortium, initiated in 2015 and financed by the National Institute of Mental Health, involves more than a dozen research centers...
Source: neuropathology blog - December 19, 2018 Category: Radiology Tags: research Source Type: blogs

Thoughts on Near Term Rejuvenation Therapies
At this year's RAADfest event, the interviewer noted here was taking an informal survey of optimistic versus pessimistic attitudes towards progress in the decades ahead. Apparently I was on the pessimistic end of the spectrum. Once past the present highly active development of senolytic therapies to remove senescent cells from old tissues, I think it quite plausible that we'll see a gap of a decade before the next class of SENS-like rejuvenation therapy arrives at the point of availability via medical tourism. The likely candidates include clearance of cross-links and restoration of the immune system via thymic regrowth. ...
Source: Fight Aging! - December 14, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Repeatedly watching a video of themselves touching a filthy bedpan reduced people ’s OCD symptoms
Another version of this new video-based smartphone intervention involved participants watching their own earlier hand washing By Emma Young Almost half of people with Obsessive Compulsive Disorder (OCD) have extreme fears about touching something they feel is “contaminated”. This can mean that after touching a doorknob, say, they then feel compelled to scrub their hands, in some cases even until they bleed. Conventional treatments, which often involve a combination of a prescription drug (typically an “SSRI”, such as Prozac) plus cognitive behavioural therapy (CBT), help only about 60 per cent of people wit...
Source: BPS RESEARCH DIGEST - November 19, 2018 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Mental health Source Type: blogs