ILC2 Immune Cells Become Altered with Age in Ways that Impair Thermoregulation
Older mammals are prone to impaired thermoregulation, such as the inability to generate sufficient warmth in response to cold temperature. Researchers here find that changes in the population of ICL2 immune cells in fat tissue are important in this dysfunction. Transplanting young immune cells into old mice appears to help, but that demonstration is just the starting point. Researchers will now have to work their way down the long road to a sufficient understanding of the underlying mechanisms to enable a cost-effective forms of intervention. How does this dysfunction connect to the underlying cell and tissue damage of agi...
Source: Fight Aging! - September 8, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Next Week ’s Conference on Retail Investing and the Future of Equities Markets
Jennifer J. SchulpRetail ––or individual––investors are having a moment. Over the past 18 months, they have entered the equities markets in droves and made headlines across the financial press. TheGameStopphenomenon got the bulk of the attention, but it is only part of the story. Retail investors opened more than10 million new brokerage accounts in 2020 and10 million more so far this year. These new investors aremore diverse, younger, and less wealthy than those who previously participated in the markets. And they not only account for asignificant portion of trading volume as of late, but they are also making a mar...
Source: Cato-at-liberty - September 1, 2021 Category: American Health Authors: Jennifer J. Schulp Source Type: blogs

The Veil of the COVID-19 Vaccination Certificates: Ignorance of Poverty, Injustice Towards the Poor
Sarah Ganty (Yale Law School), The Veil of the COVID-19 Vaccination Certificates: Ignorance of Poverty, Injustice Towards the Poor, 12 Eur. J. of Risk Regul. (forthcoming May 2021): Socioeconomic disadvantages are amplified by the COVID-19 pandemic all over the world.... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - September 1, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Pharmaceutical (Re)capture
Liza Vertinsky (Emory University), Pharmaceutical (Re)capture, Yale J. Health Pol ’y L.& Ethics (2021): This Article makes the case that pharmaceutical companies, along with other powerful corporate actors in the pharmaceutical industry, are in effect designing their own markets, often... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 19, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Cool Images: Beautiful Bits of Blue
Most cells are naturally colorless, which is why scientists often use fluorescent tags and other tools to color cell structures and make them easier to study. (Check out the Pathways imaging issue for more on scientific imaging techniques). Here, we’re showcasing cell images that feature shades of blue. Visit our Image and Video Gallery for additional images of cells in all the colors of the rainbow, as well as other scientific photos, illustrations, and videos. .featured { opacity: 1 !important; transform: scale(1) !important; z-index: 1 !important; } .featured a:hover::after { con...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 18, 2021 Category: Research Authors: Chrissa Chverchko Tags: Cells Cellular Imaging Cool Images Source Type: blogs

Reckoning with Race and Disability
Jasmine Harris (University of Pennsylvania), Reckoning with Race and Disability, 31 Yale L. J. Forum (2021) Our national reckoning with race and inequality must include disability. Race and disability have a complicated but interconnected history. Yet discussions of our most... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 12, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Eighteen Years of Monstering
 If you ' ve read Schuyler ' s Monster, you may remember the opening scene, the meeting with a neurologist at Yale at which we received Schuyler ' s Polymicrogyria diagnosis. In that scene, I described the feeling this way:At the time, when friends would attempt to comfort us by saying that at least we had an answer, at least we knew what the problem was now, I explained how it felt. Imagine walking through the woods at night, all alone. In the darkness behind you, something is following, stalking you. You can hear it disturbing the leaves as it moves, and while it never goes away, it remains hidden from view. In your...
Source: Schuyler's Monster: The Blog - July 31, 2021 Category: Disability Authors: Rob Source Type: blogs

Foresight Institute Salons on Aging Biomarkers and Clocks
The Foresight Institute folk have been quite active over the course of a year of lockdown, running virtual gatherings and regular presentations, in which you'll find more than just the usual Bay Area communities of forward-looking individuals. The interests of the Foresight Institute principals include molecular nanotechnology, artificial general intelligence, and rejuvenation biotechnology, and so you will probably find at least a few of this year's salon presentations interesting. The selection of events noted below are linked by the theme of biomarkers to measure the progression of degenerative aging. Aging is th...
Source: Fight Aging! - July 21, 2021 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Comparative Catastrophes
The building collapse in Surfside, Florida apparently killed a few more than 150 people. It has been the subject of round-the-clock coverage by every cable news network, and the front page of every newspaper, for the week since it happened. Wolf Blitzer even moved himself down there -- this is even though there has been nothing in particular new to report for 23 3/4 of every one of those round-the-clock cycles. We still aren ' t sure why it happened, and therefore unsure what larger implications there may be, if any.Meanwhile hundreds of people, at least -- we won ' t have a full appreciation of the death toll for quite a ...
Source: Stayin' Alive - July 2, 2021 Category: American Health Source Type: blogs

THCB Gang Episode 60 – Thurs July 1
Episode 60 of “The THCB Gang” was live-streamed on Thursday, July 1st. Matthew Holt (@boltyboy) was joined by policy consultant/author Rosemarie Day (@Rosemarie_Day1); THCB Editor and soon-to-be medical student at Yale, and first time #THCBGang participant Christina Liu (@ChristinayLiu) and–making a rare but welcome appearance –venture investor & soccer mogul Marcus Whitney @marcuswhitney We had a great wide ranging chat about Medicaid, venture capital and the unnecessarily excessive rigors of applying to medical school, and what that means for health equity. The video is below but if you’d rath...
Source: The Health Care Blog - July 1, 2021 Category: Consumer Health News Authors: Abdul Ghafar Tags: THCB Gang Christina Liu Marcus Whitney Matthew Holt Medicaid Medical School rosemarie day Source Type: blogs

Disability Law and HIV Criminalization
Joshua Blecher-Cohen, Disability Law and HIV Criminalization, 130 Yale L. J. (2021): Over thirty states maintain criminal laws that expressly target people living with HIV. Thousands of people are prosecuted under these statutes, exposing them to decades of incarceration, thousands... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - June 22, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Not all pain is the same
When I started working in the field of persistent pain, many of the approaches used were based on the idea that every pain was the same. Oh yes, of course we had neuropathic pain and inflammatory pain, but our treatments tended to approach each person as if they were pretty similar. We later refined that approach and started to look at people in groups. In the service I worked in, we used the Westhaven-Yale Multidimensional Pain Inventory which generates three main psychologically-based profiles – and for a long time this was a very useful way of establishing who needed the three-week residential programme, and who w...
Source: HealthSkills Weblog - May 23, 2021 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Assessment Chronic pain Clinical reasoning Pain conditions Professional topics Research Science in practice Source Type: blogs

Biden ’s Programs Would Fail for Many Reasons
Chris EdwardsPresident Biden is proposing to expand federal intervention in many areas that are the responsibility of state and local governments and the private sector. His $2.3 trillion jobsplan would subsidize broadband, automobiles, the electric grid, manufacturing, highways, transit, water systems, and much else. His $1.8 trillion familiesplan would subsidize pre ‐​school, child care, colleges, paid leave, health care, food programs, and many other things. Every dollar spent on Biden’s plans would be extracted from elsewhere in the economy through higher taxes now or in the future.Biden ’s plans would impose l...
Source: Cato-at-liberty - April 30, 2021 Category: American Health Authors: Chris Edwards Source Type: blogs

How Much Do You Want To Exercise Right Now? Researchers Are Studying People ’s In-The-Moment Motivation To Be Active
By Emma Young Think back to the last time that you did some exercise. What exactly prompted you to get up and do it? Was it because it was scheduled? Or because you felt a strong urge to engage in some physical activity (or maybe a bit of both)? Traditionally, researchers have explored a person’s general disposition to exercise, and looked at strategies to increase their exercise levels over a week, a month, or longer. However, a team led by Matt Stults-Kolehmainen at Yale University, Yale-New Haven Hospital and Columbia University argues in new work in Frontiers in Psychology that it’s also crucial to consider ...
Source: BPS RESEARCH DIGEST - April 26, 2021 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Sport Source Type: blogs

Drug Prohibition Leads to Unnecessary Deaths
David BoazI wrote an op ‐​ed aboutending the drug warin the New York Times in 1988. It ’s taking the world a long time to come around to my position. Meanwhile, the effects of prohibition persist. I complained in 1988 about 824,000 arrests a year. It wasmore than 1.6 million in 2018. I noted that the federal government was spending $3.9 billion a year on the drug war, and the figure is far higher now, thoughestimatesvary.This week ’s newspapers have reminded me of some of the less immediately obvious effects of prohibition. As with alcohol prohibition in the 1920s, it’s not enough simply ...
Source: Cato-at-liberty - April 24, 2021 Category: American Health Authors: David Boaz Source Type: blogs