Improving the physicochemical stability of Pickering emulsion stabilized by glycosylated whey protein isolate/cyanidin-3-glucoside to deliver curcumin
In this study, whey protein isolate (WPI), short-chain inulin (SCI), and cyanidin-3-glucoside (C3G) were first used to stabilize Pickering emulsions. The physicochemical properties and stability of curcumin encapsulated or not in Pickering emulsions were explored. Results showed that glycosylation and C3G reduced surface and interfacial tension on protein surfaces and inhibited the aggregation of emulsion droplets, thereby reducing the emulsion's particle size. WPI-SCI/C3G stabilized Pickering emulsion had the best stability. The CLSM results showed that the WPI-SCI and WPI-SCI/C3G stabilized emulsions were uniformly dispe...
Source: International Journal of Biological Macromolecules - December 31, 2022 Category: Biochemistry Authors: Xiaoya Tao Cheng Chen Yaochang Li Xinguang Qin Haizhi Zhang Yuanyuan Hu Zhengqi Liu Xiaoming Guo Gang Liu Source Type: research
Improving the physicochemical stability of Pickering emulsion stabilized by glycosylated whey protein isolate/cyanidin-3-glucoside to deliver curcumin
In this study, whey protein isolate (WPI), short-chain inulin (SCI), and cyanidin-3-glucoside (C3G) were first used to stabilize Pickering emulsions. The physicochemical properties and stability of curcumin encapsulated or not in Pickering emulsions were explored. Results showed that glycosylation and C3G reduced surface and interfacial tension on protein surfaces and inhibited the aggregation of emulsion droplets, thereby reducing the emulsion's particle size. WPI-SCI/C3G stabilized Pickering emulsion had the best stability. The CLSM results showed that the WPI-SCI and WPI-SCI/C3G stabilized emulsions were uniformly dispe...
Source: International Journal of Biological Macromolecules - December 31, 2022 Category: Biochemistry Authors: Xiaoya Tao Cheng Chen Yaochang Li Xinguang Qin Haizhi Zhang Yuanyuan Hu Zhengqi Liu Xiaoming Guo Gang Liu Source Type: research
Orally deliverable sequence-targeted astaxanthin nanoparticles for colitis alleviation
Biomaterials. 2022 Dec 22;293:121976. doi: 10.1016/j.biomaterials.2022.121976. Online ahead of print.ABSTRACTOrally targeted strategy of anti-inflammatory agents has attracted tremendous attention for reducing highly health-care costs and enhancing the intervention efficiency of ulcerative colitis (UC). Herein, we developed a new kind of sequence-targeted astaxanthin nanoparticles for UC treatment. Astaxanthin nanoparticles were firstly designed by self-assembly method using (3-carboxypentyl) (triphenyl) phosphonium bromide (TPP)-modified whey protein isolate (WPI)-dextran (DX) conjugates. Subsequently, lipoic acid (LA) mo...
Source: Biomaterials - December 25, 2022 Category: Materials Science Authors: Yannan Chen Wentao Su Shanshan Tie Weina Cui Xiaoting Yu Lijuan Zhang Zheng Hua Mingqian Tan Source Type: research
Orally deliverable sequence-targeted astaxanthin nanoparticles for colitis alleviation
Biomaterials. 2022 Dec 22;293:121976. doi: 10.1016/j.biomaterials.2022.121976. Online ahead of print.ABSTRACTOrally targeted strategy of anti-inflammatory agents has attracted tremendous attention for reducing highly health-care costs and enhancing the intervention efficiency of ulcerative colitis (UC). Herein, we developed a new kind of sequence-targeted astaxanthin nanoparticles for UC treatment. Astaxanthin nanoparticles were firstly designed by self-assembly method using (3-carboxypentyl) (triphenyl) phosphonium bromide (TPP)-modified whey protein isolate (WPI)-dextran (DX) conjugates. Subsequently, lipoic acid (LA) mo...
Source: Biomaterials - December 25, 2022 Category: Materials Science Authors: Yannan Chen Wentao Su Shanshan Tie Weina Cui Xiaoting Yu Lijuan Zhang Zheng Hua Mingqian Tan Source Type: research
Orally deliverable sequence-targeted astaxanthin nanoparticles for colitis alleviation
Biomaterials. 2022 Dec 22;293:121976. doi: 10.1016/j.biomaterials.2022.121976. Online ahead of print.ABSTRACTOrally targeted strategy of anti-inflammatory agents has attracted tremendous attention for reducing highly health-care costs and enhancing the intervention efficiency of ulcerative colitis (UC). Herein, we developed a new kind of sequence-targeted astaxanthin nanoparticles for UC treatment. Astaxanthin nanoparticles were firstly designed by self-assembly method using (3-carboxypentyl) (triphenyl) phosphonium bromide (TPP)-modified whey protein isolate (WPI)-dextran (DX) conjugates. Subsequently, lipoic acid (LA) mo...
Source: Biomaterials - December 25, 2022 Category: Materials Science Authors: Yannan Chen Wentao Su Shanshan Tie Weina Cui Xiaoting Yu Lijuan Zhang Zheng Hua Mingqian Tan Source Type: research
Pure-protein load for children with type 1 diabetes: is any additional insulin needed? A randomized controlled study
ConclusionsA meal containing 50 g of pure protein may be consumed without additional insulin dose. An additional square-wave bolus may be beneficial in reducing PPG. To avoid hypoglycemia, lower insulin dose should be calculated for 100 kcal from protein than for individual insulin-to-carb ratio. (Source: Acta Diabetologica)
Source: Acta Diabetologica - December 6, 2022 Category: Endocrinology Source Type: research
Molecules, Vol. 27, Pages 8509: Optimization of Wall Material of Freeze-Dried High-Bioactive Microcapsules with Yellow Onion Rejects Using Simplex Centroid Mixture Design Approach Based on Whey Protein Isolate, Pectin, and Sodium Caseinate as Incorporated Variables
Ramaswamy
For the food sector, onion rejects are an appealing source of value-added byproducts. Bioactive compounds were recovered from yellow onion rejects using a pulse electric field process at 6000 v and 60 pulses. The onion extract was encapsulated with whey protein isolate (WPI), pectin (P), and sodium caseinate (SC) with a mass ratio of 1:5 (extract/wall material, w/w). A Simplex lattice with augmented axial points in the mixture design was applied for the optimization of wall material for the encapsulation of onion reject extract by freeze-drying (FD). The optimal wall materials were 47.6 g/100g (SC), 10.0 g/10...
Source: Molecules - December 3, 2022 Category: Chemistry Authors: Elham Azarpazhooh Parvin Sharayei Xin Rui Mehranoosh Gharibi-Tehrani Hosahalli S. Ramaswamy Tags: Article Source Type: research
Structure and rheological properties of extruded whey protein isolate: Impact of inulin
Int J Biol Macromol. 2022 Nov 27:S0141-8130(22)02827-6. doi: 10.1016/j.ijbiomac.2022.11.268. Online ahead of print.NO ABSTRACTPMID:36450303 | DOI:10.1016/j.ijbiomac.2022.11.268 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - November 30, 2022 Category: Biochemistry Authors: Jinpeng Li Jiajie Yang Jingzhe Li Munkh-Amgalan Gantumur Xuan Wei Kwang-Chol Oh Zhanmei Jiang Source Type: research
Structure and rheological properties of extruded whey protein isolate: Impact of inulin
Int J Biol Macromol. 2022 Nov 27:S0141-8130(22)02827-6. doi: 10.1016/j.ijbiomac.2022.11.268. Online ahead of print.ABSTRACTImpacts of inulin addition (0, 5, 10, 15 %) on structure, functional and rheological properties of whey protein isolate (WPI) after extrusion pretreatment (E-WPI) were investigated. The results proved that after adding 15 % inulin, water holding capacity of gels, emulsifying activity, emulsion stability, foaming ability and foaming stability of E-WPI were the best and increased by 24.38 %, 7.43 %, 12.35 %, 162.97 % and 41.31 %, compared with those of unextruded WPI, respectively. Rheology analysis show...
Source: International Journal of Biological Macromolecules - November 30, 2022 Category: Biochemistry Authors: Jinpeng Li Jiajie Yang Jingzhe Li Munkh-Amgalan Gantumur Xuan Wei Kwang-Chol Oh Zhanmei Jiang Source Type: research
Enhancing the stability of oil-in-water emulsions by non-covalent interaction between whey protein isolate and hyaluronic acid
This study aimed to investigate the effect of non-covalent interactions between different concentrations (0.1-1.2 %, w/v) of hyaluronic acid (HA) and 3 % (w/v) whey protein isolate (WPI) on the stability of oil-in-water emulsions. Non-covalent interactions between WPI and HA were detected using Fourier-transform infrared spectroscopy. The addition of HA increased the electrostatic repulsion between molecules and reduced the particle size of WPI. Circular dichroism spectroscopy results indicated that the addition of HA caused an increase in β-sheet content and a decrease in α-helix and random coil content in WPI. Moreover...
Source: International Journal of Biological Macromolecules - November 22, 2022 Category: Biochemistry Authors: Ningzhe Wang Xiao Zhao Yunqing Jiang Qingfeng Ban Xibo Wang Source Type: research
Enhancing the stability of oil-in-water emulsions by non-covalent interaction between whey protein isolate and hyaluronic acid
This study aimed to investigate the effect of non-covalent interactions between different concentrations (0.1-1.2 %, w/v) of hyaluronic acid (HA) and 3 % (w/v) whey protein isolate (WPI) on the stability of oil-in-water emulsions. Non-covalent interactions between WPI and HA were detected using Fourier-transform infrared spectroscopy. The addition of HA increased the electrostatic repulsion between molecules and reduced the particle size of WPI. Circular dichroism spectroscopy results indicated that the addition of HA caused an increase in β-sheet content and a decrease in α-helix and random coil content in WPI. Moreover...
Source: International Journal of Biological Macromolecules - November 22, 2022 Category: Biochemistry Authors: Ningzhe Wang Xiao Zhao Yunqing Jiang Qingfeng Ban Xibo Wang Source Type: research
Development, characterization and probiotic encapsulating ability of novel Momordica charantia bioactive polysaccharides/whey protein isolate composite gels
In this study, a polysaccharide (MP1) with a molecular weight of 38 kDa was isolated from Momordica charantia which contains arabinose, galactose, xylose, and rhamnose. (MP1) was used to formulate composite gels with Whey Protein Isolate (WPI) that were characterized for their functional properties, microstructure, thermal resistance, probiotic encapsulating ability, and potential toward metabolic syndrome (MS). Results showed that the highest complex index was obtained at MP concentration of 2 %. MP-WPIs demonstrated superior (p < 0.05) water holding capacity and emulsifying properties than WPI gels. MP-WPIs also had h...
Source: International Journal of Biological Macromolecules - November 21, 2022 Category: Biochemistry Authors: Awa Fanny Massounga Bora Kouadio Jean Eric-Parfait Kouame Xiaodong Li Lu Liu Yue Sun Qian Ma Yibo Liu Source Type: research
Development, characterization and probiotic encapsulating ability of novel Momordica charantia bioactive polysaccharides/whey protein isolate composite gels
In this study, a polysaccharide (MP1) with a molecular weight of 38 kDa was isolated from Momordica charantia which contains arabinose, galactose, xylose, and rhamnose. (MP1) was used to formulate composite gels with Whey Protein Isolate (WPI) that were characterized for their functional properties, microstructure, thermal resistance, probiotic encapsulating ability, and potential toward metabolic syndrome (MS). Results showed that the highest complex index was obtained at MP concentration of 2 %. MP-WPIs demonstrated superior (p < 0.05) water holding capacity and emulsifying properties than WPI gels. MP-WPIs also had h...
Source: International Journal of Biological Macromolecules - November 21, 2022 Category: Biochemistry Authors: Awa Fanny Massounga Bora Kouadio Jean Eric-Parfait Kouame Xiaodong Li Lu Liu Yue Sun Qian Ma Yibo Liu Source Type: research
Starch and whey protein isolate films including an aroma compound stabilized by nanocellulose
This study aimed to prepare whey protein isolate (WPI) and starch (S) films, including nanocellulose based BO nanoemulsions, potentially enhancing BO functionality. BO nanoemulsion was obtained by using a nanocellulose dispersion (2 mg/mL) including 3 mM CaCl2 with a ratio of 2/8 (v/v, BO/nanocellulose dispersion) and then suitably dispersed (2%, w/w) in the WPI and S film-forming solutions to obtain film samples. The water vapor permeability (WVP), mechanical and optical properties and BO's release from those obtained films were studied. The WVP (p<0.05) and tensile strength (p>0.05) of films were improved, whereas ...
Source: An Acad Bras Cienc - November 9, 2022 Category: Science Authors: Ece Sogut Atif Can Seydim Source Type: research
Starch and whey protein isolate films including an aroma compound stabilized by nanocellulose
This study aimed to prepare whey protein isolate (WPI) and starch (S) films, including nanocellulose based BO nanoemulsions, potentially enhancing BO functionality. BO nanoemulsion was obtained by using a nanocellulose dispersion (2 mg/mL) including 3 mM CaCl2 with a ratio of 2/8 (v/v, BO/nanocellulose dispersion) and then suitably dispersed (2%, w/w) in the WPI and S film-forming solutions to obtain film samples. The water vapor permeability (WVP), mechanical and optical properties and BO's release from those obtained films were studied. The WVP (p<0.05) and tensile strength (p>0.05) of films were improved, whereas ...
Source: An Acad Bras Cienc - November 9, 2022 Category: Science Authors: Ece Sogut Atif Can Seydim Source Type: research
