Smoking cessation integrated with a lung cancer screening program: most effective method?
Conclusions: Smoking cessation and LCS associated seem to increase the probability of smoking cessation. It is recommended to associate a LCS program with a smoking cessation program as this encourages smoking cessation. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Nunez, A., Baeza, S., Cervera, E., Rodriguez, L., Gonzalez, A., Garcia Olive, I., Chirinos, R., Andreo, F., Rosell, A. Tags: Lung cancer Source Type: research

Effect of next-step antidepressant treatment on suicidal ideation: findings from the VAST-D trial
CONCLUSION: SI declines for most patients during next-step medication treatments. But about 1 in 5 experienced emergent or worsening SI during treatment, so vigilance for suicide risk through the entire 12-week acute treatment period is necessary. Treatment selection may affect the risk of SI.PMID:37859623 | DOI:10.1017/S0033291723003008 (Source: Psychological Medicine)
Source: Psychological Medicine - October 20, 2023 Category: Psychiatry Authors: Sidney Zisook Christine Yu Moutier A John Rush Gary R Johnson Ilanit Tal P J Chen Lori L Davis Paul B Hicks James Wilcox Beata Planeta Kimberly Weingart Lauro Alexandra A Scrymgeour John Kasckow Somaia Mohamed Source Type: research

Increased depression-like behaviors with altered brain dopamine metabolisms in male mice housed in large cages are alleviated by bupropion
Eur J Pharmacol. 2023 Oct 17:176126. doi: 10.1016/j.ejphar.2023.176126. Online ahead of print.ABSTRACTPsycho-environmental stress-based animal models of anxiety and depression are useful for investigating pathological mechanisms and drug development. Although several rodent-based studies have reported the beneficial effects of environmental enrichment (EE) on brain plasticity and anxiety- and depression-like behaviors, other studies have reported inverse effects. Here, we found that housing male mice in EE involving large cages and other EE materials increased anxiety- and depression-like behaviors in open field and tail s...
Source: European Journal of Pharmacology - October 20, 2023 Category: Drugs & Pharmacology Authors: Kaito Kurogi Fuka Taniguchi Ryohei Matsuo Marina Shinozuka Raiki Suzaki Shinobu Yasuo Source Type: research

Effect of next-step antidepressant treatment on suicidal ideation: findings from the VAST-D trial
CONCLUSION: SI declines for most patients during next-step medication treatments. But about 1 in 5 experienced emergent or worsening SI during treatment, so vigilance for suicide risk through the entire 12-week acute treatment period is necessary. Treatment selection may affect the risk of SI.PMID:37859623 | DOI:10.1017/S0033291723003008 (Source: Psychological Medicine)
Source: Psychological Medicine - October 20, 2023 Category: Psychiatry Authors: Sidney Zisook Christine Yu Moutier A John Rush Gary R Johnson Ilanit Tal P J Chen Lori L Davis Paul B Hicks James Wilcox Beata Planeta Kimberly Weingart Lauro Alexandra A Scrymgeour John Kasckow Somaia Mohamed Source Type: research

Increased depression-like behaviors with altered brain dopamine metabolisms in male mice housed in large cages are alleviated by bupropion
Eur J Pharmacol. 2023 Oct 17:176126. doi: 10.1016/j.ejphar.2023.176126. Online ahead of print.ABSTRACTPsycho-environmental stress-based animal models of anxiety and depression are useful for investigating pathological mechanisms and drug development. Although several rodent-based studies have reported the beneficial effects of environmental enrichment (EE) on brain plasticity and anxiety- and depression-like behaviors, other studies have reported inverse effects. Here, we found that housing male mice in EE involving large cages and other EE materials increased anxiety- and depression-like behaviors in open field and tail s...
Source: European Journal of Pharmacology - October 20, 2023 Category: Drugs & Pharmacology Authors: Kaito Kurogi Fuka Taniguchi Ryohei Matsuo Marina Shinozuka Raiki Suzaki Shinobu Yasuo Source Type: research