Effect of next-step antidepressant treatment on suicidal ideation: findings from the VAST-D trial

CONCLUSION: SI declines for most patients during next-step medication treatments. But about 1 in 5 experienced emergent or worsening SI during treatment, so vigilance for suicide risk through the entire 12-week acute treatment period is necessary. Treatment selection may affect the risk of SI.PMID:37859623 | DOI:10.1017/S0033291723003008

Source: Psychological Medicine - October 20, 2023 Category: Psychiatry Authors: Sidney Zisook Christine Yu Moutier A John Rush Gary R Johnson Ilanit Tal P J Chen Lori L Davis Paul B Hicks James Wilcox Beata Planeta Kimberly Weingart Lauro Alexandra A Scrymgeour John Kasckow Somaia Mohamed Source Type: research