Vitamin B6, leukemia's deadly addiction
(Cold Spring Harbor Laboratory) Researchers from CSHL and Memorial Sloan Kettering Cancer Center have discovered how Acute Myeloid Leukemia is addicted to vitamin B6. Now that researchers know this, they can pursue new treatment options for the deadly blood cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 13, 2020 Category: Cancer & Oncology Source Type: news
Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism
The human gut microbiota metabolizes the Parkinson’s disease medication Levodopa (l-dopa), potentially reducing drug availability and causing side effects. However, the organisms, genes, and enzymes responsible for this activity in patients and their susceptibility to inhibition by host-targeted drugs are unknown. Here, we describe an interspecies pathway for gut bacterial l-dopa metabolism. Conversion of l-dopa to dopamine by a pyridoxal phosphate-dependent tyrosine decarboxylase from Enterococcus faecalis is followed by transformation of dopamine to m-tyramine by a molybdenum-dependent dehydroxylase from Eggerthell...
Source: ScienceNOW - June 12, 2019 Category: Science Authors: Maini Rekdal, V., Bess, E. N., Bisanz, J. E., Turnbaugh, P. J., Balskus, E. P. Tags: Chemistry, Microbiology, Online Only r-articles Source Type: news
High Vitamin B6, B12 May Increase Hip Fracture Risk High Vitamin B6, B12 May Increase Hip Fracture Risk
A combined high intake of vitamins B6 and B12 was linked to an increased hip fracture risk, a study found.Medscape Medical News (Source: Medscape ObGyn and Womens Health Headlines)
Source: Medscape ObGyn and Womens Health Headlines - May 17, 2019 Category: OBGYN Tags: Internal Medicine News Source Type: news
Too much vitamin B6 and B12 tied to hip fractures in older women
Older women who take supplements with high doses of vitamins B6 and B12 may be more likely than their counterparts who don't to experience hip fractures, a U.S. study suggests. (Source: Reuters: Health)
Source: Reuters: Health - May 15, 2019 Category: Consumer Health News Tags: healthNews Source Type: news
Are Onions and Garlic Healthy? Here ’s What Experts Say
Garlic and onions are staples for many home cooks. But do these plants actually add any health benefits to your dishes? Or are they purely for flavor?
People who try to eat colorful fruits and vegetables in order to get a wide range of vitamins and minerals may think that pale foods like onions and garlic don’t offer many nutrients. But although they may not look like nutritional powerhouses, experts say they are.
Onions of all colors (including white) are good sources of vitamin C, vitamin B6, potassium and folate, while garlic is rich in vitamin C, vitamin B6, thiamin, potassium, calcium, phosphorous, copper and ma...
Source: TIME: Health - May 15, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition Source Type: news
Are Mushrooms Healthy? Here ’s What Experts Say
The versatile mushroom comes in all different shapes, sizes and colors; it stands up as a side and can replace meat as a main. The fungus is a favorite of nutrition professionals — packed with vitamins, minerals and other nutrients.
Here’s what mushrooms can do for your health, and how to work them into your diet.
What are the nutritional benefits of mushrooms?
Mushrooms are a low-carb, practically no-fat food with some protein. One serving is about a cup raw (a fist-sized amount) or 1/2 cup cooked.
Though they’re small and light in calories—one serving only has about 15—they’re mighty i...
Source: TIME: Health - January 31, 2019 Category: Consumer Health News Authors: Cassie Shortsleeve Tags: Uncategorized Diet/Nutrition Source Type: news
Are Sweet Potatoes Healthy? Here ’s What Experts Say
Sweet potatoes pack the unique health benefits of regular potatoes with a little something extra. “In general, the more color you can add into your diet coming from fruits and vegetables, the better,” says Yasi Ansari, a sports dietitian in Los Angeles and San Francisco.
Still, the many nutritional benefits are no excuse to spring for sweet potato fries at every chance.
Here’s what you need to know about how healthy sweet potatoes are, plus the best ways to incorporate them into any diet.
What are the nutritional benefits of sweet potatoes?
“All potatoes are nutrient-dense and healthy for you,&rdquo...
Source: TIME: Health - January 10, 2019 Category: Consumer Health News Authors: Cassie Shortsleeve Tags: Uncategorized Diet/Nutrition Source Type: news
Food Poisoning by Ginkgo Seeds through Vitamin B6 Depletion - Kobayashi D.
Overconsumption of Ginkgo biloba seeds induces food poisoning characterized by tonic-clonic convulsions and vomiting. The primary toxic component, 4'-O-methylpyridoxine (MPN), was purified from the seeds in 1985. This review includes the following aspects ... (Source: SafetyLit)
Source: SafetyLit - January 7, 2019 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news
Are Pistachios Healthy? Here ’s What Experts Say
You can find the shelled green nuts everywhere, from airport kiosks to health food stores. But are pistachios as healthy as they’re cracked up to be? Here’s what the experts say.
What are the nutrition facts of pistachios?
Pistachios are packed with vitamins, minerals and nutrients, including beta carotene, phosphorus, vitamin B6, thiamine, potassium, magnesium and fiber. Compared to other nuts, they are also high in carotenoids, a type of antioxidant that helps reduce the risk of chronic disease and improves heart health, says registered dietitian Kristin Kirkpatrick.
You can also eat a lot of them in just one...
Source: TIME: Health - September 20, 2018 Category: Consumer Health News Authors: Cassie Shortsleeve Tags: Uncategorized Diet/Nutrition healthytime Source Type: news
Carbonyl catalysis enables a biomimetic asymmetric Mannich reaction
Chiral amines are widely used as catalysts in asymmetric synthesis to activate carbonyl groups for α-functionalization. Carbonyl catalysis reverses that strategy by using a carbonyl group to activate a primary amine. Inspired by biological carbonyl catalysis, which is exemplified by reactions of pyridoxal-dependent enzymes, we developed an N-quaternized pyridoxal catalyst for the asymmetric Mannich reaction of glycinate with aryl N-diphenylphosphinyl imines. The catalyst exhibits high activity and stereoselectivity, likely enabled by enzyme-like cooperative bifunctional activation of the substrates. Our work demonstr...
Source: ScienceNOW - June 28, 2018 Category: Science Authors: Chen, J., Gong, X., Li, J., Li, Y., Ma, J., Hou, C., Zhao, G., Yuan, W., Zhao, B. Tags: Chemistry reports Source Type: news
A melatonin-fueled drink to help you sleep: What a nutritionist says about the trend
Som Sleep contains melatonin, magnesium, vitamin B6, GABA and L-theanine. (Source: ABC News: Health)
Source: ABC News: Health - June 25, 2018 Category: Consumer Health News Tags: GMA Source Type: news
Diclegis (Doxylamine Succinate and Pyridoxine Hydrochloride Delayed-release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 13, 2018 Category: Drugs & Pharmacology Source Type: news
Vitamin B6 deficiency: Six foods to add to your diet to avoid the development of symptoms
VITAMIN B6, also known as pyridoxine, plays an important role in the function of the body. Like other B vitamins, it helps maintain a healthy metabolism, never function, liver function, skin health and eye health. While a deficiency is rare in the western world, you should make sure you get enough and keep symptoms at bay by eating these six vitamin B6 rich foods. (Source: Daily Express - Health)
Source: Daily Express - Health - May 15, 2018 Category: Consumer Health News Source Type: news
Vitamin B6 supplements may help people recall their dreams
Researchers from The University of Adelaide found that taking a strong dose of such supplements for just five days improves people's abilities to remember their dreams by 64 per cent. (Source: the Mail online | Health)
Source: the Mail online | Health - April 27, 2018 Category: Consumer Health News Source Type: news
Super-strength vitamin B6 supplements may help people recall their DREAMS
Researchers from The University of Adelaide found that taking a strong dose of such supplements for just five days improves people's abilities to remember their dreams by 64 per cent. (Source: the Mail online | Health)
Source: the Mail online | Health - April 27, 2018 Category: Consumer Health News Source Type: news
