TWiV 745: Gorilla COVID with Nadine Lamberski
Nadine Lamberski joins TWiV to discuss an outbreak of COVID-19 among gorillas at the San Diego Zoo, and the use of a spike protein-based vaccine to immunize the animals. Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker Guest: Nadine Lamberski Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Gorillas receive COVID-19 vaccine (Nat Geo) COVID-19 vaccine for great apes and mink (Zoetis) Letters read on TWiV 745 Timestamps by Jolene. Thanks! Weekly Picks Brianne – The Dream Vaccine Alan – Taking vaccines to Smith Island Kathy – Daily Ove...
Source: This Week in Virology - MP3 Edition - April 18, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 739: COVID-19 convalescent plasma with Arturo Casadevall
Arturo Casadevall joins TWiV to discuss the use of convalescent plasma to treat COVID-19, including a history of the process, how plasma is prepared and tested, why it is difficult to conduct randomized clinical trials, how this treatment has fared and his hopes for the future. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Guest: Arturo Casadevall Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Victory for Scientific Pragmatism (New Atlantis) Convalescent plasma levels and risk of COVID-19 death (NEJM) COVID-19 convalescent plasma safety ...
Source: This Week in Virology - MP3 Edition - April 4, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Don ’t think too deeply about the origin of life – it may have started in puddles
How water chemistry is shifting researchers' thoughts on where life might have arisen, and a new model to tackle climate change equitably and economically.In this episode:00:46 A shallow start to life on Earth?It’s long been thought that life on Earth first appeared in the oceans. However, the chemical complexities involved in creating biopolymers in water has led some scientists to speculate that shallow pools on land were actually the most likely location for early life.News Feature: How the first life on Earth survived its biggest threat — water07:44 CoronapodThe COVID-19 pandemic has massively shifted the scientifi...
Source: Nature Podcast - December 9, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Don ’t think too deeply about the origin of life – it may have started in puddles
How water chemistry is shifting researchers' thoughts on where life might have arisen, and a new model to tackle climate change equitably and economically.In this episode:00:46 A shallow start to life on Earth?It’s long been thought that life on Earth first appeared in the oceans. However, the chemical complexities involved in creating biopolymers in water has led some scientists to speculate that shallow pools on land were actually the most likely location for early life.News Feature: How the first life on Earth survived its biggest threat — water07:44 CoronapodThe COVID-19 pandemic has massively shifted the scientifi...
Source: Nature Podcast - December 9, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Neutrinos give insights into the workings of the Sun ’s core
Scientists have finally confirmed the existence of a CNO cycle fusion reaction in the Sun, and why women’s contraception research needs a reboot.In this episode:00:47 Detection of CNO neutrinosSince the 1930s it has been theorised that stars have a specific fusion reaction known as the CNO cycle, but proof has been elusive. Now, a collaboration in Italy report detection of neutrinos that show that the CNO cycle exists.Research article: The Borexino CollaborationNews and Views: Neutrino detection gets to the core of the Sun08:48 CoronapodWe discuss the search for the animal origin of SARS-CoV-2, with researchers raiding t...
Source: Nature Podcast - November 25, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Neutrinos give insights into the workings of the Sun ’s core
Scientists have finally confirmed the existence of a CNO cycle fusion reaction in the Sun, and why women’s contraception research needs a reboot.In this episode:00:47 Detection of CNO neutrinosSince the 1930s it has been theorised that stars have a specific fusion reaction known as the CNO cycle, but proof has been elusive. Now, a collaboration in Italy report detection of neutrinos that show that the CNO cycle exists.Research article: The Borexino CollaborationNews and Views: Neutrino detection gets to the core of the Sun08:48 CoronapodWe discuss the search for the animal origin of SARS-CoV-2, with researchers raiding t...
Source: Nature Podcast - November 25, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 672: Black in Microbiology with Ari Kozik and Kishana Taylor
Ari and Kishana, two of the founders of Black in Microbiology, join TWiV to discuss the goals of the organization, then we review pauses of J&J and Lilly COVID-19 vaccine trials, preclinical studies of Regeneron's SARS-CoV-2 monoclonal antibody cocktail, reinfection of a patient in Nevada, and listener questions. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker Guest: Ari Kozik and Kishana Taylor Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Black microbiologists push for visibility (NY Times) Black in Microbiology keynotes (YouTube) ...
Source: This Week in Virology - MP3 Edition - October 15, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 626: Ralph Baric and fancy ferrets
Daniel Griffin provides a clinical update on COVID-19, then Ralph Baric joins TWiV to discuss SARS-CoV-2 transmission, vaccines, diagnostic tests, and a new animal model from his laboratory that does not use transgenic mice. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guests: Daniel Griffin, Chuck Knirsch, and Ralph Baric Subscribe (free): iTunes, Google Podcasts, RSS, email Links for this episode Mouse-adapted SARS-CoV-2 model (bioRxiv) SARS-CoV-2 mRNA vaccine (bioRxiv) ASM resources for #shutdownstem President Obama on sustaining momentum for change (Facebook) America Af...
Source: This Week in Virology - MP3 Edition - June 14, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 598: Who was that masked man? Coronavirus update with Daniel Griffin
Daniel Griffin MD returns to TWiV from a hospital parking lot to provide updates on COVID-19 diagnostics, clinical picture, and therapeutics, followed by our coverage of the coronavirus pandemic caused by SARS-CoV-2. Hosts: Vincent Racaniello, Dickson Despommier,Rich Condit, and Kathy Spindler Guest: Daniel Griffin, MD Download TWiV 598 (70 MB .mp3, 115 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Restricted dispensing of Plaquenil in NY state Virology of COVID-19 patients (Nature) Susceptibility of domestic animals to SARS-CoV-2 (bioRxiv_ Cloth face ma...
Source: This Week in Virology - MP3 Edition - April 5, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 590: COVID-19 and coronavirus - we have mail
The TWiV trio continues in-depth coverage of COVID-19 and SARS-CoV-2, including discussion on genome mutation and circulating lineages, handwashing, facemasks, cruise ship outbreaks, the South Korean situation, and much more. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Stanley Perlman answers CoV questions (Boston Globe) Fist bump (Am J Infect Control) Joint WHO-China report (pdf) Second coronavirus (LA Times) Response to second coronavirus (virological.org) COVID-19 animal models (STAT) Clinical pr...
Source: This Week in Virology - MP3 Edition - March 8, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 573: Inventing viruses
William Summers joins the TWiV team to discuss some virology history, including the ever-changing concept of 'virus' and the contribution of phage research to the study of animal viruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit Guest: William Summers Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Bill’s ASV 2019 talk (PPT download) Inventing viruses (Ann Rev Virol) Timestamps by Jolene. Thanks! Weekly Science Picks Alan - Restoration of Western Flyer Rich - Purification of phage T7 RNA polymerase Dickson - The Galaxy is Not F...
Source: This Week in Virology - MP3 Edition - November 10, 2019 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 494: Ebola Makona is the opposite of hakuna matata
Vincent, Kathy, and Alan review the ongoing outbreak of Ebola virus in the Democratic Republic of the Congo, and the finding that mutations identified in the 2015 West African epidemic do not alter pathogenesis in animals. Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Microbe 2018 Support Viruses & Cells Gordon Conference Faculty positions at Icahn School of Medicine International dsRNA Virus Symposium New Ebola virus outbreakin DRC (WHO) Ebola virus case in urban area of DRC(WHO) Ebola virus outbreak not PHEIC(WHO) Ebola virus vaccinearrives in DRC (CIDR...
Source: This Week in Virology - MP3 Edition - May 20, 2018 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

MVA85A trial investigation - press conference.
Trial MVA85A - monkey trials for a booster vaccine for BCG, developed by researchers at Oxford University, is the subject of an investigation published on bmj.com. Experts warn that today’s investigation is just one example of “a systematic failure” afflicting preclinical research and call for urgent action “to make animal research more fit for purpose as a valuable and reliable forerunner to clinical research in humans.” The press conference is l ed by Dr Fiona Godlee, the editor-in-chief of the BMJ, who provides a background to the investigation. The panel members are: Dr Deborah Cohen, author of the invest...
Source: The BMJ Podcast - January 11, 2018 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts