TWiV 912: COVID-19 clinical update #120 with Dr. Daniel Griffin
In COVID-19 clinical update #120, Dr. Griffin discusses outcomes of SARS-CoV-2 reinfection, CDC recommendation for vaccines in young children, neurodevelopment outcomes in infants of mothers testing positive for COVID during pregnancy, efficacy of monoclonal antibodies and antivirals in hamsters, rebound phenomenon after PAXLOVID in high-risk persons, hospitalization for infection after PAXLOVID treatment, and risk of long COVID with different variants. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Reinfection outcomes (Research Square) CDC recommends v...
Source: This Week in Virology - MP3 Edition - June 25, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: USA authorises vaccines for youngest of kids
After a long wait, the US Food and Drug Administration (FDA) and Centres for Disease Control and Prevention (CDC) have finally approved two COVID vaccines for use in children between the ages of six months and five years old. But despite a unanimous decision amongst regulators, parents still have questions about whether to vaccinate their young children, with survey data suggesting that the majority do not intend to accept vaccines right away. In this episode of Coronapod, we dig into the trials, the statistics and the regulators decision making process, in search of clarity around what the data are saying.News:&...
Source: Nature Podcast - June 24, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 911: Antibody can get vaccinated now
TWiV provides an update on hepatitis of unknown etiology in children, an experimental nanoparticle vaccine for Epstein-Barr virus, and minimal impact of bamlanivimab therapy on antiviral antibodies induced by vaccination. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Hepatitis of unknown etiology (MMWR) Clinical recognition of monkeypox (CDC) Epstein-Barr virus nanoparticle vaccine (Cell Rep Med) Minimal impact of mAb therapy on COVID vaccine induced antibodies (Sci Trans Med) L...
Source: This Week in Virology - MP3 Edition - June 19, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 910: COVID-19 clinical update #119 with Dr. Daniel Griffin
In COVID-19 clinical update #119, Dr. Griffin reviews tixagevimab for infection prevention, ivermectin for outpatient infection treatment, symptom rebound after PAXLOVID treatment, bamlanivimab minimally impacting immune response to vaccination, in-hospital mortality among infection patients, residual viral antigen in patients following infection, usage of Casirvimab/Imdevimab and Remdesivir in infected patients with depleted B-cells, and rheumatic symptoms following infection. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Tixagevimab-Cilgavimab for i...
Source: This Week in Virology - MP3 Edition - June 18, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Talk Evidence - political persuasion and mortality, too much medicine
In this week's episode, Helen Macdonald is joined by Joseph Ross, US research editor for The BMJ, and Juan Franco, editor of BMJ EBM. They begin by discussing a review of obesity interventions in primary care, and Joe wonders if GPs are really the best people to tackle the issue. https://www.bmj.com/content/377/bmj-2021-069719 Cervical screening in the UK now includes HPV testing, and they look at research which examines wheth er this could mean longer periods between screening tests. https://www.bmj.com/content/377/bmj-2021-068776 They all enjoy a new State of the Art Review into Revascularization in stable coronary...
Source: The BMJ Podcast - June 17, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk Evidence - political persuasion and mortality, too much medicine
In this week's episode, Helen Macdonald is joined by Joseph Ross, US research editor for The BMJ, and Juan Franco, editor of BMJ EBM. They begin by discussing a review of obesity interventions in primary care, and Joe wonders if GPs are really the best people to tackle the issue. https://www.bmj.com/content/377/bmj-2021-069719 Cervical screening in the UK now includes HPV testing, and they look at research which examines whether this could mean longer periods between screening tests. https://www.bmj.com/content/377/bmj-2021-068776 They all enjoy a new State of the Art Review into Revascularization in stable coronary a...
Source: The BMJ Podcast - June 17, 2022 Category: General Medicine Authors: BMJ Group Source Type: podcasts

How the Black Death got its start
00:46 Uncovering the origins of the Black DeathThe Black Death is estimated to have caused the deaths of up to 60% of the population of Europe. However, despite extensive research, the origin of this wave of disease has remained unclear. Now, by using a combination of techniques, a team have identified a potential starting point in modern day Kyrgyzstan.Research article: Spyrou et al.06:57 Research HighlightsThe cocktails of toxins produced by wriggling ribbon worms, and a tiny thermometer the size of a grain of sand.Research Highlight: A poisonous shield, a potent venom: these worms mean businessResearch Highlight: Mighty...
Source: Nature Podcast - June 15, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Varenicline and African American Smokers, COVID-19 Vaccination in Children and Adolescents, Digital Breast Tomosynthesis vs Digital Mammography, and more
Editor's Summary by by Anne Cappola, MD, Associate Editor of JAMA, the Journal of the American Medical Association, for the June 14, 2022 issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - June 14, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 908: COVID-19 clinical update #118 with Dr. Daniel Griffin
In COVID-19 clinical update #118, Dr. Griffin discusses management of hair loss after infection, FDA announcements on vaccine schedule and recommendations, Moderna announcement on bivalent booster candidate, association between vaccination and infection during pregnancy, population-level implications of Israel’s booster campaign, PAXLOVID outcomes during recent infection surge, efficacy and safety of Tixagevimab-cilgavimab, diagnostic accuracy of infection by canines, efficacy of colchicine in hospitalized patients, and factors associated with hospital readmission.   Subscribe (free): Apple Podcasts, Google Podcasts,...
Source: This Week in Virology - MP3 Edition - June 11, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 906: Long COVID, giant viruses, and smallish pox
TWiV reviews human monkeypox infections, evidence for human Mimivrus infections, and incidence of long COVID in post-vaccine SARS-CoV-2 infections. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Monkeypox update (ProMedMail) Multi-country monkeypox outbreak (WHO) Monkeypox new global threat (Science) Monkeypox outbreak 9 US states (MMWR) Mimivirus in human respiratory samples (Sci Rep) Long COVID after post-vaccination infection (Nat Med) Letters read on TWiV 906 Timestamps b...
Source: This Week in Virology - MP3 Edition - June 5, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 905: COVID-19 clinical update #117 with Dr. Daniel Griffin
In COVID-19 clinical update #117, Dr. Griffin discusses duration of virus shedding, association between pre-exposure to steroids and infection outcome, post-infection subtypes, rehabilitation for post-acute infection, Tixagevimab/Cilgavimab for infection prevention, antibody prophylaxis and vaccination in kidney transplant recipients, remdesivir and bebtelovimab fact sheets for providers, the updated guidelines on treatment with Famotidine, Paxlovid rebound symptom characterizations, antigen test positivity duration, viral dynamics of variants and isolation, association of inflammation in CS fluid, and transmission dynami...
Source: This Week in Virology - MP3 Edition - June 4, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Robot exercises shoulder cells for better tissue transplants
00:47 The robot shoulder that exercises cellsRecreating the movements that tendon cells experience as they develop in the human body is necessary for growing tissue for transplantation, but this has been difficult to achieve in a laboratory setting. Now, a team has developed a system that uses a robot shoulder to stretch and twist these cells, which they hope could be used to improve the quality of tissue grafts in the future.Research article: Mouthuy et al.Video: A robotic Petri dish: How to grow human cells in a robot shoulder07:56 Research HighlightsA robotic surgeon that works within an MRI chamber, and an ancient huma...
Source: Nature Podcast - June 1, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 903: COVID-19 clinical update #116 with Dr. Daniel Griffin
In COVID-19 clinical update #115, Dr. Griffin discusses croup association with infection surge, rhinovirus co-circulation in children, shedding following vaccination, high vaccine efficacy in children 6 mo-5 yr, vaccine protection for hospitalized patients, convalescent plasma as post-exposure prophylaxis, real-world effectiveness of PAXLOVID, effectiveness of PAXLOVID in reducing hospitalization, infection rebound after PAXLOVID, relapse of symptomatic infection after PAXLOVID, remdesivir and bebtelovimab fact sheets for providers, guidelines on usage of anticoagulation drugs, long covid symptoms after vaccina...
Source: This Week in Virology - MP3 Edition - May 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 901: COVID-19 clinical update #115 with Dr. Daniel Griffin
In COVID-19 clinical update #115, Dr. Griffin reviews cross-variant immunity without vaccination, EUA for boosters in 5-11 year olds, B.1.1.529 attack rate, scent dogs, Omicron and pets, Paxlovid, Veklury, Fluvoxamine, antigen positivity after isolation, inflammasome activation and severe disease, and GI persistence and fecal shedding. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Limited cross-variant immunity without vaccination (Nature) EUA for boosters in 5-11 year olds (FDA) Stages of COVID-19 (AIDS Rev) B.1.1.529 attack rate in Australia (JID) Sce...
Source: This Week in Virology - MP3 Edition - May 21, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 900: Burning down the mouse
TWiV celebrates 900 episodes, Vincent gives the Richard R. Ernst lecture, and we discuss why inflammasome activation in infected macrophages drives severe COVID-19. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Richard R. Ernst Lecture Infected macrophages drives severe COVID-19 (Nature) Timestamps by Jolene. Thanks! Weekly Picks Brianne – The Milky Way’s Black Hole Comes to Light Kathy – River dolphins playing with anaconda Rich – Smallpox vaccination techniq...
Source: This Week in Virology - MP3 Edition - May 15, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts