TWiV 925: First kisses and second doses
TWiV discusses monkeypox virus, poliovirus in NY, Marburg virus in Ghana, ancient herpes simplex virus type 1 genomes, and immunogenicity of different combinations of SARS-CoV-2 vaccines. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode How monkeypox virus spreads (CDC) Vaccination against monkeypox virus (CDC) Monkeypox case trends (CDC) Polio in New York State (NY Dept of Health) Poliovirus in NY wastewater (NBC New York) Marburg disease in Ghana (WHO) Ancient herpesvi...
Source: This Week in Virology - MP3 Edition - August 7, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 924: TWiV clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Tecovirimat for treatment of monkeypox, the safety and acceptance of vaccination after multisystem inflammatory syndrome, variants in solid organ transplant recipients, masks for prevention of respiratory virus infections, pre-exposure prophylaxis with Evusheld, the association between Evusheld administration and infection, if repeat administration of casirivimab and imdevimab is well-tolerated, viral and symptom rebound in untreated infection, extended Remdesivir infusion for persistent infection, Baricitinib in patients admitted with infection, and cognitive impa...
Source: This Week in Virology - MP3 Edition - August 6, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Long COVID: The US Federal Response
On August 3, 2022, the US Department of Health and Human Services released 2 major reports in response to a presidential memo calling for a whole-of-government response to the SARS-CoV-2 sequelae known as “Long COVID." JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses these new reports and the research and support needed to address this pervasive health concern with HHS Assistant Secretary for Health Rachel Levine, MD. Recorded July 29, 2022. Related Content: Addressing the Long-term Effects of COVID-19 Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalizat...
Source: JAMA Author Interviews - August 3, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts
Talk Evidence - shoulders, knees, and woes
In this episode, Juan Franco, editor in chief of BMJ EBM, and Helen Macdonald, The BMJ's research integrity editor, sit down to discuss what's new in the world of evidence.
Firstly, last week they went to the first EBM Live conference for two years - and report back on what happened when the evidence community got back together.
We have two research papers looking at knees and shoulders, and finding out about the balance of risks and benefits.
In covid news, we're still finding new symptoms associated with infection, 2.5 years after the pandemic started. We'll also hear how complex it is to research vaccine efficacy now...
Source: The BMJ Podcast - July 31, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts
Talk Evidence - shoulders, knees, and woes
In this episode, Juan Franco, editor in chief of BMJ EBM, and Helen Macdonald, The BMJ's research integrity editor, sit down to discuss what's new in the world of evidence.
Firstly, last week they went to the first EBM Live conference for two years - and report back on what happened when the evidence community got back together.
We have two research papers looking at knees and shoulders, and finding out about the balance of risks and benefits.
In covid news, we're still finding new symptoms associated with infection, 2.5 years after the pandemic started. We'll also hear how complex it is to research vaccine efficacy now...
Source: The BMJ Podcast - July 31, 2022 Category: General Medicine Authors: BMJ Group Source Type: podcasts
TWiV 922: TWiV clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses monkeypox infection in humans across 16 countries, pregnancy outcomes after SARS-CoV-2 infection by trimester, vaccination intent and belief, antiviral drug treatment for non-severe disease, the association of smoking with infected hospitalized patients, the association of Paxlovid on negative conversion rates among high-risk patients with COVID-19, safety and efficacy of Molnupiravir, usage of enoxaparin for primary thromboprophylaxis, statin and aspirin as therapy in infected patients, post-COVID-19 conditions among children 90 days after SARS-CoV-2 Infection, and sympt...
Source: This Week in Virology - MP3 Edition - July 30, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Coronapod: the open-science plan to unseat big Pharma and tackle vaccine inequity
Inequity has been a central feature of the COVID19 pandemic. From health outcomes to access to vaccines, COVID has pushed long-standing disparities out of the shadows and into the public eye and many of these problems are global. In this episode of Coronapod we dig into a radical new collaboration of 15 countries - led by the UN, and modelled on open-science. The project, called the mRNA vaccine technology transfer hub, aims to create independent vaccine hubs that could supply the global south, and take on the giants of the pharmaceutical industry in the process. But the road ahead is long - the challenges are co...
Source: Nature Podcast - July 29, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts
TWiV 921: COVID-19 clinical update #124 with Dr. Daniel Griffin
In COVID-19 clinical update #124, Dr. Griffin discusses the results of a variant vaccine booster trial, the neutralization of variant sub-lineages by Novavax, the CDC’s recommendation of Novavax’s COVID-19 vaccine in adults, Paxlovid in patients who are immunocompromised and hospitalized, and inhaled fluticasone for outpatient treatment. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Variant vaccine boosters trial (medRxiv) Novavax triggers neutralization of variant sub-lineages (bioRxiv) CDC recommends Novavax (CDC) Paxlovid in patients who ar...
Source: This Week in Virology - MP3 Edition - July 23, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 919: Motivated by volatiles
TWiV reviews the FDA decision to update COVID-19 vaccine boosters in the fall, the meaning of fatigue with respect to long COVID, and a skin volatile induced by flavivirus reproduction that attracts mosquitoes to the infected host. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID-19 vaccine booster composition (FDA) Settling in for the long haul (Crooked Timber) Flavivirus-induced skin volatile attracts mosquitoes (Cell) Letters read on TWiV 919 Timestamps by Jolene. Thanks! ...
Source: This Week in Virology - MP3 Edition - July 17, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 918: COVID-19 clinical update #123 with Dr. Daniel Griffin
In COVID-19 clinical update #123, Dr. Griffin discusses rapid diagnostic testing in response to the monkeypox outbreak, leading causes of death in the US during the COVID-19 pandemic, antibody evasion by subvariants, broadly-neutralizing antibodies against emerging variants, factors associated with severe outcomes among hospitalized immunocompromised adults, measurement of the burden of hospitalizations during the pandemic, parental vaccine hesitancy in diverse communities, evaluating saliva sampling to improve access to diagnosis in low-resource settings, oral sabizabulin for high-risk hospitalized adults, lower-risk of m...
Source: This Week in Virology - MP3 Edition - July 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 917: Boosters on, Paul Offit
Paul Offit returns to TWiV to discuss why, during the recent FDA advisory committee meeting, he voted against releasing revised COVID-19 vaccines containing an Omicron component, and the reasons why children must be vaccinated against the disease. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode 28 June 2022 VRBPAC meeting materials (FDA) Don’t rush to change COVID vaccines (STAT) Materials from 28 June FDA advisory meeting (FDA) Letters read on TWiV 917 Tim...
Source: This Week in Virology - MP3 Edition - July 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 916: COVID-19 clinical update #122 with Dr. Daniel Griffin
In COVID-19 clinical update #122, Dr. Griffin discusses vaccine availability and coverage among children, post-infection health impairments in children and adolescents, infection detection using salvia and nasopharyngeal samples, effectiveness of vaccines during delta dominance, durability of vaccine against severe outcomes, concern in the postvaccination era, infection rebound after Paxlovid & Molnupiravir, lack of improvement after adding ivermectin to standard care, duration of shedding of virus, how thromboprophylaxis reduces thromboembolism but increases major bleeding, multi-lineage neural and myelin dysregulation ca...
Source: This Week in Virology - MP3 Edition - July 9, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 915: Mouse mouth to mouse mom
TWiV discusses the recent decision by an FDA advisory committee to update COVID vaccines for the fall, the monkeypox virus outbreak, and the finding that enteric viruses infect the salivary glands and are transmitted through saliva. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Postdoctoral position in the Kielian Laboratory (pdf) COVID vaccine update for fall (WaPo) Don’t rush to change COVID vaccines (STAT) Materials from 28 June FDA advisory meeting (FD...
Source: This Week in Virology - MP3 Edition - July 3, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 914: COVID-19 clinical update #121 with Dr. Daniel Griffin
In COVID-19 clinical update #121, Dr. Griffin discusses age as a risk factor for severe disease, updated vaccine boosters for the fall, pediatric infection and antibody seroprevalence in Arkansas over the first year of the COVID-19 pandemic, all-cause maternal mortality in the United States before and during the pandemic, and the effect of 2-week interruption in methotrexate treatment and how it impacts vaccine immunity. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Age as a risk factor for severe disease (NY Times) Omicron boosters for the fall (NPR) P...
Source: This Week in Virology - MP3 Edition - July 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 913: Twinkle twinkle little SARS
TWiV explains the meaning of vaccine-derived poliovirus found in London sewage, risk of long COVID after infections with Delta or Omicron variants of SARS-CoV-2, and enhancers of innate immune signaling as broad-spectrum antivirals. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Poliovirus in UK sewage (ProMedMail and Science) Poliovirus eradication effort (Science) Long COVID after Delta and Omicron (Lancet) How common is long COVID? (Nature) Immune enhancers as ...
Source: This Week in Virology - MP3 Edition - June 26, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
